Charles Piller
speaker
984 appearances
4 recordings
4 series
first heard Mar 2025
last heard 17 Apr
Charles Piller’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Apr 2026 with 1.
Appearances
nature basically sat on this literally for more than almost two years before doing anything about it and actually more than two years it turned out to be now what they did is they kicked it back to the university of minnesota this is the institution with the most to lose and the least to gain from doing a robust complete and publicly accessible examination of concerns about one of its scientists research and
Lo and behold, they went years investigating this.
Ultimately, the study was retracted, but we didn't get the details of what the University of Minnesota's investigation was.
We didn't get those details because they behaved in an incredibly secretive way.
I might add that ultimately Sylvain Lesnay, who was implicated in being most involved with the apparent image doctoring in this study,
was retired out of the university, even though he was a young, full professor there.
Very unusual, but clearly substantial problem that caused him to retire.
Well, let me put it this way.
So I want to make it clear that I agree that amyloid proteins and tau proteins have something to do with Alzheimer's disease.
I think where I part ways with the progenitors and supporters of the amyloid hypothesis as the dominant way of looking at the disease is that I don't think they have everything to do with Alzheimer's disease.
And I think that the way in which that idea has been promoted has squeezed out other ways of thinking about Alzheimer's.
because of the scarcity of funding, when so much emphasis goes on one dominant set of ideas, it can be hard for other researchers to get traction in their way of thinking about the disease.
I think that is the sort of tragedy of the issue.
If I could just expand on that briefly, there has been an enormous amount of fraud and misconduct in the field of Alzheimer's disease, a lot of it associated with the amyloid hypothesis.
that is in part because the dominant way of thinking about the disease presents a big target and it makes the possibility of incorrect or falsified information more likely to be accepted by the scientific community.
If it fits,
with the dominant way of thinking about disease, even if it's wrong, even if it's based on fraud or misconduct, it's much more likely to pass muster and to be seen as being correct information.
But I want to say briefly that
Fraud and misconduct is still, in my view, a small part of the overall scientific equation.
Most scientists, like most people in all walks of life, are honest and deeply committed to doing the right thing to develop human knowledge and to serve humanity in a beneficial way.
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