Charles Piller
speaker
984 appearances
4 recordings
4 series
first heard Mar 2025
last heard 17 Apr
Charles Piller’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Apr 2026 with 1.
Appearances
And there's trials going on right now, again, that I think within a few years might have fruitful information that could prove beneficial in understanding the possibility that there's other avenues involved.
maybe in concert with the amyloid hypothesis or maybe separate from it, that could have a lot of impact in helping, if not cure people, at least helping the cognitive symptoms become less bad or be arrested in some way. Now, there's one other thing I wanted to mention, Dylan, and I know this is most certainly an interest of yours, which is prevention.
And one of the things that I feel hopeful about is that it's becoming more known nationally and globally that We do have agency in our lives, even when it comes to a dreaded disease like Alzheimer's that sometimes seems so mysterious. We know very well that there are certain things that are risk factors for the disease, things like high blood pressure, high cholesterol,
sedentary lifestyles where people don't get exercise, or eating habits where people aren't getting the proper mix of nutrition and eating well. I guess what I'm trying to say is that living our best lives
aside from it being its own benefit, aside from it being something we might all want to do just for the sake of, again, having our best lives, it can also be a way of forestalling or lessening the effects of Alzheimer's disease late in life should we be one of the unlucky ones to get that disease as an older person. So I'm just encouraging people to think positively and
to take precautions, to address risk factors, and to live your best lives for all kinds of reasons, including prevention.
And what we need is creative thinking that supplements some of the more conventional studies to keep people moving in being broad minded about it. Now, you know, I just want to make it clear that while I'm not an expert in. Things like supplements and brain training and things like that. I'm not aware of anything like that that is either a preventive or a cure for the disease.
Beyond what I've already said, that I think generally taking care of risk factors is good for all of us. for whatever ails you, not just Alzheimer's disease. But I want to say that I appreciate what you're saying because I think creative thinking, innovative thinking is part of what's going to solve this problem ultimately.
It may be, and I think many scientists think that Alzheimer's is a multifactorial kind of disease. In other words, there might be a number of causes and it might require more than one approach. to really arrest the symptoms of cognitive decline.
And therefore, some of the things you're saying, like neuroinflammation, there are many scientists in the field who believe that that may be one of the linchpins of both comprehending the origins of the disease and doing something useful for people that have it. So the short answer is yes, people should be looking at these things.
I don't personally know the research you're talking about, so I don't have an opinion on it, but creative thinking is what we need.
Oh, you're so kind to say that, Dylan. And I just want to say that I agree with you very much. We have to remember that we are the center of our own lives. And we're the protagonists in our own stories. And it's up to us to think creatively and be thoughtful and to take care of ourselves. And I appreciate what you're doing towards that as well.
Well, it is available through every normal online source, of course, and through your local bookstore. People prefer to do it that way. I like to support local bookstores. And you can find an enormous amount of information about the book if you want to hear what people are saying about it. There have been a lot of reviews, a lot of articles about it, other podcasts.
I encourage you to, if you're interested beyond what we've talked about, there's other different specialty podcasts that have talked about it. And those are all listed on my website. Very simple, charlespilleroneword.com.
Uh, I'm on blue sky and, uh, X and, uh, LinkedIn. And yes, I look at, I look at postings. If you, uh, if you tag me, I'll see it at some point. And, uh, uh, depending on how busy that day is. Uh, but yes, and, uh, feel free to reach out. There's also my contact information is, uh, up on my website as well. So you don't have to, to scurry around to find it on those social media sites.
Sounds terrific. Thanks again for all your interest. And I've enjoyed talking about this with you, Dylan.
Science and medicine sometimes have an arrogance problem. They use the idea that trust us or the experts. All across the United States, school buildings sit empty. Unfortunately, that trust has to be won, not just assumed. Often scientists are entrusted with policy decisions for which they have no specific expertise or decisions about how to run things in society.
They might claim expertise for it, but they actually have no special expertise for it. And those are the reasons why I think sometimes people develop mistrust in science.
In this episode, I sit down with Charles Piller, the investigative journalist for Science Magazine, who is behind some of the biggest exposés on scientific fraud. His recent book, Doctored, has uncovered widespread corruption by self-interested researchers, government accomplices, and greedy corporations, all racing in the quest to cure Alzheimer's.
We discuss secret data manipulations, shocking misconduct, and the unsettling truth about how money and prestige can derail real progress. But it's not all doom and gloom. We also dive in into how we can rebuild trust and make science work better for everyone. So sit back, get comfortable, and let's jump right into this eye-opening conversation.
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