Charlotte MacDonald
speaker
1,889 appearances
62 recordings
1 series
first heard Sep 2010
last heard Apr 2025
Charlotte MacDonald’s voice in public audio — every appearance, attributed to the second.
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Appearances
outing me like this on the radio?
Well, I appreciate it now, I guess, but growing up, I always ran the risk of being bullied or, you know, being burned at the stake for witchcraft.
Did you grow up in medieval Europe?
Well, actually, it was the East Midlands in the 80s.
I'm sure it's the same thing.
But anyway, whilst running the risk of some bullying, it turns out redheads could actually have a special ability.
Our secret ingredient, MC1R.
No, that's my chemical romance.
MC1R is a gene.
In fact, it's the thing that makes most of us redheads in the first place.
I'll let Professor Geoff Mogill explain.
He's the Canada Research Chair in Genetics of Pain.
Well, that's a Jeff living up to his title of Chair in Genetics of Pain.
His team wondered whether the reason that redheads needed fewer opioids could be because the MC1R gene already acted as a natural pain inhibitor.
So they joined up with a team in the Netherlands to electrocute redheads.
Wait, what?
Only a bit, though.
Not quite.
A paper published around the same time found that redheaded mice were more sensitive to thermal pain, so hot and cold temperatures.
I don't know, but I do know that there could be two reasons for redheads having higher pain tolerance for one thing and not the other.
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