Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

Chris Masterjohn

๐Ÿ‘ค Speaker
1255 total appearances

Appearances Over Time

Podcast Appearances

The Joe Rogan Experience
#2420 - Chris Masterjohn

Quite a bit of it is in heart disease.

The Joe Rogan Experience
#2420 - Chris Masterjohn

It looks pretty promising in various forms of heart disease.

The Joe Rogan Experience
#2420 - Chris Masterjohn

But if you look at

The Joe Rogan Experience
#2420 - Chris Masterjohn

that literature, what you see is a dose response where at 1 to 200 milligrams per day of CoQ10, the average person's glucose, insulin, and blood pressure looks better than not taking it.

The Joe Rogan Experience
#2420 - Chris Masterjohn

But the average person at 400 milligrams of CoQ10 is actually having worse blood pressure, glucose, and insulin than they were without taking it.

The Joe Rogan Experience
#2420 - Chris Masterjohn

And the variability around that is huge.

The Joe Rogan Experience
#2420 - Chris Masterjohn

So one person is probably gonna be worse at 100 milligrams, whereas another person might get their best

The Joe Rogan Experience
#2420 - Chris Masterjohn

at 400 milligrams, but it's like, if you looked at the literature and you would say, where is the sweet spot where the average person is gonna be doing really good, it would be 100 to 200 milligrams a day.

The Joe Rogan Experience
#2420 - Chris Masterjohn

But I think there are,

The Joe Rogan Experience
#2420 - Chris Masterjohn

I've seen a lot of edge cases on either side where some people get miracles and some people get, I wouldn't say catastrophe, but they just get worse off.

The Joe Rogan Experience
#2420 - Chris Masterjohn

So a lot of people complain about insomnia, they complain about their heart racing or heart palpitations, various things like that, overstimulation, feeling like the lights are too bright or the sounds are too strong or whatever, just hypersensory awareness.

The Joe Rogan Experience
#2420 - Chris Masterjohn

It's not common, but it's I mean all the people don't common stuff always ask me about it's right at higher levels or No, I know I just like a hundred milligrams like normal.

The Joe Rogan Experience
#2420 - Chris Masterjohn

They're just hypersensitive people out there Okay, and then is this rare is this like I don't know how common it is.

The Joe Rogan Experience
#2420 - Chris Masterjohn

So what I mean what I can tell you is that Across the trials

The Joe Rogan Experience
#2420 - Chris Masterjohn

You see some people reporting GI side effects, which is super common.

The Joe Rogan Experience
#2420 - Chris Masterjohn

You don't see a lot of this mentioned, but you never know if they were looking for it.

The Joe Rogan Experience
#2420 - Chris Masterjohn

Like a lot of times the side effect list is dependent on what side effects they asked about.

The Joe Rogan Experience
#2420 - Chris Masterjohn

I think for some people that have complained about insomnia, they have thought that it was worse when they took it in the evening.

The Joe Rogan Experience
#2420 - Chris Masterjohn

Makes sense, right?

The Joe Rogan Experience
#2420 - Chris Masterjohn

Well, you know, OK, so I think let me set the stage for this with just kind of like