David Ghiyam
👤 SpeakerAppearances Over Time
Podcast Appearances
Less than 1%.
Less than 1%.
That's better than declining every day. Yeah, but even a reduction in the rate of decline would have been game-changing. That's what was observed in the Alzheimer's patients. Wow. Their rate of decline, they continue to decline, but their rate of decline was markedly reduced, far more so than in the drugs that have become FDA approved that target beta amyloid.
That's better than declining every day. Yeah, but even a reduction in the rate of decline would have been game-changing. That's what was observed in the Alzheimer's patients. Wow. Their rate of decline, they continue to decline, but their rate of decline was markedly reduced, far more so than in the drugs that have become FDA approved that target beta amyloid.
That number is probably around 75%. Wow. Is that diabetic or pre-diabetic? Both.
That number is probably around 75%. Wow. Is that diabetic or pre-diabetic? Both.
Really, it depends on the blood sugar measurement, where the cutoff is specifically for diabetes, which is a marker, not only measures blood sugar, but also looks at something called the hemoglobin A1C.
Really, it depends on the blood sugar measurement, where the cutoff is specifically for diabetes, which is a marker, not only measures blood sugar, but also looks at something called the hemoglobin A1C.
Pre-diabetic or diabetic. And I think that it's unfortunate that we use that terminology because we get to the discussion of, you know, when you go to the doctor and look at your blood sugar or look at yourself, if you have a continuous glucose monitor, you know what your blood sugar is and you're going to ask yourself, well, what's normal?
Pre-diabetic or diabetic. And I think that it's unfortunate that we use that terminology because we get to the discussion of, you know, when you go to the doctor and look at your blood sugar or look at yourself, if you have a continuous glucose monitor, you know what your blood sugar is and you're going to ask yourself, well, what's normal?
And I think in healthcare, we've been looking at what's so-called normal range, what's in the normal range for a long time. And I think that doesn't really serve the notion of optimal health very well. Normal may not be healthy still. Normal is what's common, basically. You take a large number of people, you see what is normal? Our population isn't normal.
And I think in healthcare, we've been looking at what's so-called normal range, what's in the normal range for a long time. And I think that doesn't really serve the notion of optimal health very well. Normal may not be healthy still. Normal is what's common, basically. You take a large number of people, you see what is normal? Our population isn't normal.
Our population, as we discussed earlier, is not healthy. We should define what is optimal. And so, you know, typically a doctor would say, well, your blood sugar is a hundred or 105 and everything's fine. We'll see in next year and check again, a very static measurement of your blood sugar fasting that you'll probably train for a little bit. So you can get a good number.
Our population, as we discussed earlier, is not healthy. We should define what is optimal. And so, you know, typically a doctor would say, well, your blood sugar is a hundred or 105 and everything's fine. We'll see in next year and check again, a very static measurement of your blood sugar fasting that you'll probably train for a little bit. So you can get a good number.
And I really want to know what is your worst blood sugar? What is the level of blood sugar at its worst and how long does it stay elevated after carbohydrate challenge? What is, as we talked about off camera, what is over time the area under the curve? In other words, when we look at the level of blood sugar over time, it defines an area.
And I really want to know what is your worst blood sugar? What is the level of blood sugar at its worst and how long does it stay elevated after carbohydrate challenge? What is, as we talked about off camera, what is over time the area under the curve? In other words, when we look at the level of blood sugar over time, it defines an area.
And that's really a very valuable metric in terms of understanding the dynamics of blood sugar and how insulin is working in your body which is one of the fundamentals for metabolic health. Because the brain by and large powers itself with glucose.
And that's really a very valuable metric in terms of understanding the dynamics of blood sugar and how insulin is working in your body which is one of the fundamentals for metabolic health. Because the brain by and large powers itself with glucose.
The higher the glucose over time, the less the brain is able to use it because the brain becomes, many parts of the brain depend upon insulin to allow the glucose to be used as fuel. As we threaten the function of insulin by virtue of the fact that our blood sugar remains elevated over time, we threaten the brain. We threaten the mitochondria.
The higher the glucose over time, the less the brain is able to use it because the brain becomes, many parts of the brain depend upon insulin to allow the glucose to be used as fuel. As we threaten the function of insulin by virtue of the fact that our blood sugar remains elevated over time, we threaten the brain. We threaten the mitochondria.