David Ghiyam

So having said that, it's a clear and present danger. And mechanistically, we've already covered why it happens because we're threatening mitochondria. We're threatening to change those wonderful supportive immune cells to becoming the evil twin and destroying brain cells. And, you know, it all comes together. We are now connecting these dots.

So having said that, it's a clear and present danger. And mechanistically, we've already covered why it happens because we're threatening mitochondria. We're threatening to change those wonderful supportive immune cells to becoming the evil twin and destroying brain cells. And, you know, it all comes together. We are now connecting these dots.

My colleague, Dr. Robert Lustig, has really gone a long way to really defining the biochemistry in terms of how this is happening. And then what are then these relationships between these dietary trends and brain health decline? But yet, we're seeing ever-increasing amounts of other information kind of leading us to believe that, well, there are bad sugars and good sugars.

My colleague, Dr. Robert Lustig, has really gone a long way to really defining the biochemistry in terms of how this is happening. And then what are then these relationships between these dietary trends and brain health decline? But yet, we're seeing ever-increasing amounts of other information kind of leading us to believe that, well, there are bad sugars and good sugars.

And the reality is that the most threatening sugar of all is not glucose. What is it? It is fructose. By far and away. What's the difference between glucose and fructose? So they are totally different molecules in terms of the number of carbon atoms. And importantly, in table sugar, it's both. It's 50% fructose and 50% glucose. They are bonded together.

And the reality is that the most threatening sugar of all is not glucose. What is it? It is fructose. By far and away. What's the difference between glucose and fructose? So they are totally different molecules in terms of the number of carbon atoms. And importantly, in table sugar, it's both. It's 50% fructose and 50% glucose. They are bonded together.

We consume that table sugar and then we, in the intestine with an enzyme called sucrase, we break it up into fructose and glucose. Fructose doesn't require insulin for its metabolism, and as we may have talked about before, immediately is metabolized into something called uric acid, which is a profound threat to our metabolism. Glucose is absorbed and is used as fuel.

We consume that table sugar and then we, in the intestine with an enzyme called sucrase, we break it up into fructose and glucose. Fructose doesn't require insulin for its metabolism, and as we may have talked about before, immediately is metabolized into something called uric acid, which is a profound threat to our metabolism. Glucose is absorbed and is used as fuel.

Fructose is a powerful mitochondrial toxin. Toxin. Mitochondrial toxin. Fructose. Fruit sugar, fructose. Now, having said that table sugar is 50% fructose, recognize that there exists something out there called high fructose corn syrup, which has an even higher percentage of fructose that is cheap and really, really sweet.

Fructose is a powerful mitochondrial toxin. Toxin. Mitochondrial toxin. Fructose. Fruit sugar, fructose. Now, having said that table sugar is 50% fructose, recognize that there exists something out there called high fructose corn syrup, which has an even higher percentage of fructose that is cheap and really, really sweet.

which is why it's the go-to sweetener for about 60 to 70% of grocery store shelf packaged products contain at least some added sweetener. By and large, it's high fructose corn syrup or a derivative thereof. Fructose is a powerful threat to our immune function, a powerful threat to mitochondrial health. That's why it threatens our immune function.

which is why it's the go-to sweetener for about 60 to 70% of grocery store shelf packaged products contain at least some added sweetener. By and large, it's high fructose corn syrup or a derivative thereof. Fructose is a powerful threat to our immune function, a powerful threat to mitochondrial health. That's why it threatens our immune function.

and clearly a clear and present danger as it relates to brain health and Alzheimer's risk. So let me take us back, let me wind the clock back a little bit to when we started today. You presented some very sobering statistics about not just where we are in Alzheimer's, but where we're going.

and clearly a clear and present danger as it relates to brain health and Alzheimer's risk. So let me take us back, let me wind the clock back a little bit to when we started today. You presented some very sobering statistics about not just where we are in Alzheimer's, but where we're going.

I think you talked about 2050 with tripling of the prevalence of Alzheimer's at that time, far outstripping the aging of our population. And I think the query was, why is it happening? And my response to you was, because of the changes in our metabolic health. The number one threat to our metabolic health, and I believe I said it before, is our fructose consumption.

I think you talked about 2050 with tripling of the prevalence of Alzheimer's at that time, far outstripping the aging of our population. And I think the query was, why is it happening? And my response to you was, because of the changes in our metabolic health. The number one threat to our metabolic health, and I believe I said it before, is our fructose consumption.

And indeed, humans consume fruit sugar. It goes by the name of fructose. That's where the name comes from. And we can handle at any given time about five grams of fructose. That's an apple. One apple a day? No, at a time. At a time.

And indeed, humans consume fruit sugar. It goes by the name of fructose. That's where the name comes from. And we can handle at any given time about five grams of fructose. That's an apple. One apple a day? No, at a time. At a time.

You can have a couple of apples in a day, but you don't want to load your body, you don't want to load your digestive system quickly with any more than about five grams of fructose.

You can have a couple of apples in a day, but you don't want to load your body, you don't want to load your digestive system quickly with any more than about five grams of fructose.