David Olson
👤 PersonAppearances Over Time
Podcast Appearances
A lot of times people will describe synthetic organic chemists as molecular architects. And what we do is really not a whole lot different than what an architect does. The only difference is we can't see what we are building.
A lot of times people will describe synthetic organic chemists as molecular architects. And what we do is really not a whole lot different than what an architect does. The only difference is we can't see what we are building.
This is really calming for me. But in many neuropsychiatric and neurodegenerative conditions, it looks like wintertime. You know, all of the leaves have fallen off the trees. The arborist has come in and pruned back all the branches. And now there's not that physical connectivity between adjacent neurons.
This is really calming for me. But in many neuropsychiatric and neurodegenerative conditions, it looks like wintertime. You know, all of the leaves have fallen off the trees. The arborist has come in and pruned back all the branches. And now there's not that physical connectivity between adjacent neurons.
This is really calming for me. But in many neuropsychiatric and neurodegenerative conditions, it looks like wintertime. You know, all of the leaves have fallen off the trees. The arborist has come in and pruned back all the branches. And now there's not that physical connectivity between adjacent neurons.
moving us more towards a healing-based approach, where if you take a drug once or a few times, that could lead to long-lasting therapeutic benefit. So now you're not thinking about taking a drug every single day for the rest of your life. You can take the drug, have this healing effect, and then not have to take it continually.
moving us more towards a healing-based approach, where if you take a drug once or a few times, that could lead to long-lasting therapeutic benefit. So now you're not thinking about taking a drug every single day for the rest of your life. You can take the drug, have this healing effect, and then not have to take it continually.
moving us more towards a healing-based approach, where if you take a drug once or a few times, that could lead to long-lasting therapeutic benefit. So now you're not thinking about taking a drug every single day for the rest of your life. You can take the drug, have this healing effect, and then not have to take it continually.
We need to have something that is so safe that you can simply pick it up at your local pharmacy, bring it home, and put it in your medicine cabinet.
We need to have something that is so safe that you can simply pick it up at your local pharmacy, bring it home, and put it in your medicine cabinet.
We need to have something that is so safe that you can simply pick it up at your local pharmacy, bring it home, and put it in your medicine cabinet.
And if the drug needs to be administered in the clinic under the supervision of multiple healthcare professionals, we're just never going to be able to reach all those patients.
And if the drug needs to be administered in the clinic under the supervision of multiple healthcare professionals, we're just never going to be able to reach all those patients.
And if the drug needs to be administered in the clinic under the supervision of multiple healthcare professionals, we're just never going to be able to reach all those patients.
Fortunately, that's what medicinal chemists are very good at. They can take a chemical structure and tweak it just a little bit to improve its properties.
Fortunately, that's what medicinal chemists are very good at. They can take a chemical structure and tweak it just a little bit to improve its properties.
Fortunately, that's what medicinal chemists are very good at. They can take a chemical structure and tweak it just a little bit to improve its properties.
And as researchers started to study it more, they realized that ketamine produced very rapid antidepressant effects, effects that appeared within 24 hours as opposed to the couple of weeks that you would need for an SSRI. And this was really paradigm shifting for the field.
And as researchers started to study it more, they realized that ketamine produced very rapid antidepressant effects, effects that appeared within 24 hours as opposed to the couple of weeks that you would need for an SSRI. And this was really paradigm shifting for the field.
And as researchers started to study it more, they realized that ketamine produced very rapid antidepressant effects, effects that appeared within 24 hours as opposed to the couple of weeks that you would need for an SSRI. And this was really paradigm shifting for the field.