Derek (More Plates More Dates)

they're going to be in the ground.

And if they're not, it kind of indicates that you don't have adequate either androgen or estrogen signaling.

It would be odd if you're on testosterone replacement and your LH and FSH weren't like at the bottom of the barrel.

It would almost be questioning at that point, like, am I having something inhibit the androgens from working or the estrogen?

Because it's like you could theoretically blunt estrogen mediated feedback by using, you know, an aromatase inhibitor or a CIRM or something and like blunt that response.

and you would see in your blood work it'd be like your body still thinks it needs to make more natural testosterone and you know it's kicking up the gonadotropin so if you're on like true replacement those levels should be like not like even present essentially um which is odd like seeking to have like a bottom note number as like what the target is um that would kind of indicate you've definitely kind of like satisfactory replaced to what you need to stimulate like the negative feedback

um yeah and i mentioned the lipids um yeah i'm definitely missing something but fasting insulin some of the insulin resistance markers and um there's some stuff you should probably check like baseline like clotting risks you know predispositions uh factor five laden you know things like this um

LP little a at baseline, especially because androgens suppress LP little a uniquely, which a lot of people don't realize is affected by androgens, which is typically not something that can be manipulated through anything really that I'm aware of through like diet and lifestyle.

So you might think you have like a,

I don't know, you might have like a, think you have a better Lp little a than you actually had at baseline.

So like your genetics might be like masked a bit by your androgen use.

I don't know, thyroid balance, you know, thyroid levels are good to have.

How much TSH do you have?

You know, T4, T3, the free balance of those hormones.

IGF-1.

None of these are like critical necessarily, but they're just worth having for basic health assessments and to see where you land.

But like, yeah, it's basically like your total test, your free test, your estradiol, the free levels, sensitive assay measurements, LHFSH, hematology, HDL, kind of like the basics, metabolic health, insulin sensitivity metrics, I think are kind of like the critical baseline ones.

Well, fortunately, a lot of good panels will just have it for you.

It's not like you would ever be expected to remember all that stuff.

And I'm probably missing it.