Derek (More Plates More Dates)

There are some fringe cases in men where, okay, you might have a nutrient deficiency or you might have some weird genetic predisposition that was totally corrected by adding in fill in the blank thing or you had undiagnosed hypothyroidism or what have you.

Typically not the case.

Typically it's pattern hair loss, miniaturization of the hair follicle.

And if a lot of people, unfortunately, get misled by these like crazy, you know, wild stories like, oh, the solution's on the horizon.

Oh, just like wipe some broccoli on your head.

Oh, do this.

and they just lose their hair and there's no recovering because unfortunately what happens is if you leave it for too long the area starts to undergo fibrosis so it's not like it's something that you can necessarily recover to baseline if you're completely slick bald the scalp environment is no longer habitable to like healthy hair follicles that are like you know your original hair you're not gonna grow it back probably until they start like cloning hair follicles or something

So you kind of got to get in front of it, similar to ASCVD, as absurd as it sounds, like before it starts stacking because it's something that's cumulative and insidious and over time, eventually, all of a sudden, it's a problem.

So when you're young, you know, why is it?

This is one of the stupidest things I hear.

Why is it that when your DHT levels are at their highest, when you're young, you have no hair loss, but then when you're old, you have hair loss.

It's like the same reason that you've been stacking plaque in your arteries since you were like a teenager.

Like it's cumulative.

So being preventative and proactive is the name of the game when it comes to hair loss.

And yeah,

I'm not to say that like there isn't a solution that exists in the planet that somehow addresses the downstream cascade of like, you know, TGF beta and like, you know, the the WNT pathway, all this fringe stuff that is a result of the androgen induced transcriptional activity.

But at the end of the day, nothing seems to be potent enough to attenuate whatever is happening downstream.

So like the net result is the follicle literally like starves itself and miniaturizes.

Like the follicle becomes weaker, thinner, and over time, the antigen phase, which is like the growth phase of the hair follicle,

shortens shortens shortens and over time you're just like shedding weaker and weaker hair and it's growing back thinner and thinner and eventually it's so thin sparse and insignificant cosmetically that you can't even see it and it's just like these follicles have essentially died and gone undergone literal apoptosis because each one is an organ in itself individually and once it dies like it's not gonna just come back from the dead and then that area