Dr. Adeel Khan

And so a better term for it that Arnold Kaplan, who's the guy who coined the term mesenchymal stem cells in 1992, he's the guy who coined it. He wrote a paper about this, but basically he said that these things should be called committed progenitor cells, which is

And so a better term for it that Arnold Kaplan, who's the guy who coined the term mesenchymal stem cells in 1992, he's the guy who coined it. He wrote a paper about this, but basically he said that these things should be called committed progenitor cells, which is

a fancy word for just saying that they can't turn into new tissue, that they can reduce inflammation, which can still be useful in some conditions, but it's just misleading because a lot of patients are like, oh yeah, I got stem cell injections. It's like, well, it wasn't really a stem cell per se. It was more just something to reduce inflammation because it's not

a fancy word for just saying that they can't turn into new tissue, that they can reduce inflammation, which can still be useful in some conditions, but it's just misleading because a lot of patients are like, oh yeah, I got stem cell injections. It's like, well, it wasn't really a stem cell per se. It was more just something to reduce inflammation because it's not

Because remember, the definition of a stem cell is something that can actually regenerate new tissue. And if you're just taking your fat or your bone marrow and injecting it, that's not regenerating new tissue through the mechanism of that stem cell. It may send signals to your own body stem cells to help with some regeneration. But for the most part, it's an anti-inflammatory product.

Because remember, the definition of a stem cell is something that can actually regenerate new tissue. And if you're just taking your fat or your bone marrow and injecting it, that's not regenerating new tissue through the mechanism of that stem cell. It may send signals to your own body stem cells to help with some regeneration. But for the most part, it's an anti-inflammatory product.

And so that's the number one thing to understand about these. And this is, we're talking about the broader category of mesenchymal stem cells, which is just, you know, an embryological term. But essentially what it means is this is from, you know, the reason we use mesenchymal stem cells is because they're the easiest to source.

And so that's the number one thing to understand about these. And this is, we're talking about the broader category of mesenchymal stem cells, which is just, you know, an embryological term. But essentially what it means is this is from, you know, the reason we use mesenchymal stem cells is because they're the easiest to source.

because they're in the fat, they're in the bone marrow, they're from the medical core tissue or dental pulp. There's so many different sources now. But that's the reason why MSCs or mesenchymal stem cells are so popular. And the other reason is because mesenchymal stem cells only have a finite ability to differentiate which means they can they won't cause tumors or cancer.

because they're in the fat, they're in the bone marrow, they're from the medical core tissue or dental pulp. There's so many different sources now. But that's the reason why MSCs or mesenchymal stem cells are so popular. And the other reason is because mesenchymal stem cells only have a finite ability to differentiate which means they can they won't cause tumors or cancer.

Of course, that's always been a concern with like embryonic stem cells, which if you're taking them from aborted fetuses, which some clinics still do. And obviously during the Bush era, there was a lot of controversy around that. And that's why stem cells kind of got categorized into this unethical thing. But that's not how we're sourcing our stem cells. We're sourcing them.

Of course, that's always been a concern with like embryonic stem cells, which if you're taking them from aborted fetuses, which some clinics still do. And obviously during the Bush era, there was a lot of controversy around that. And that's why stem cells kind of got categorized into this unethical thing. But that's not how we're sourcing our stem cells. We're sourcing them.

You know, obviously we're not we're not harming any babies and they're being sourced from C-section births after, you know, and some instead of being thrown away, they're donated. So it's a very simple collection process.

You know, obviously we're not we're not harming any babies and they're being sourced from C-section births after, you know, and some instead of being thrown away, they're donated. So it's a very simple collection process.

But the problem with the mesenchymal stem cells, as we said, is first of all, there's a lot of clinics saying that they're taking your fat and bone marrow and claiming their stem cells, which are not. But let's say, let's say you go offshore somewhere and they can isolate them and then they can do what's called culture expansion, which means they can grow them and they can replicate them.

But the problem with the mesenchymal stem cells, as we said, is first of all, there's a lot of clinics saying that they're taking your fat and bone marrow and claiming their stem cells, which are not. But let's say, let's say you go offshore somewhere and they can isolate them and then they can do what's called culture expansion, which means they can grow them and they can replicate them.

So then they can actually have some sort of dose that can be a therapeutic and potentially regenerate tissue in theory. But then again, What happened, it turns out, when you take these stem cells, whether from any of these sources, when you put them in the body, most of them don't survive. And when you do them intravenously, most of them get trapped in the lungs or die.

So then they can actually have some sort of dose that can be a therapeutic and potentially regenerate tissue in theory. But then again, What happened, it turns out, when you take these stem cells, whether from any of these sources, when you put them in the body, most of them don't survive. And when you do them intravenously, most of them get trapped in the lungs or die.

And that's why the results have been very inconsistent. And that's why stem cells haven't taken off the way we thought they would, you know, 10, 15 years ago. And that's why the clinical trials have been so mixed. Uh, and so unfortunately there's still a lot of clinics claiming that, you know, we can regenerate tissue. You can do it.

And that's why the results have been very inconsistent. And that's why stem cells haven't taken off the way we thought they would, you know, 10, 15 years ago. And that's why the clinical trials have been so mixed. Uh, and so unfortunately there's still a lot of clinics claiming that, you know, we can regenerate tissue. You can do it.