Dr. Allen Bookatz
speaker
1,037 appearances
12 recordings
1 series
first heard May 2026
last heard 4d ago
Dr. Allen Bookatz’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 12 in all, peaking in Sep 2026 with 4.
Appearances
They don't just circulate the bloodstream.
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They actually
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Get to the brain.
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And that's really scary.
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They reach the brain.
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And there's this these little organs that are technically, I guess, not part of the brain, but where the blood brain barrier is actually quite permeable.
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And they call them the circumventricular organs there.
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And they're just a a a specialized grouping of brain structures.
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But once inside, they're they have this, they have like this direct access to uh the microglia.
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And I don't know about you, but I think of like the micro.
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As the brain's own like immune patrol.
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So normally they're like hanging out, they're quiet, they're in maintenance mode.
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And then you know, the blood brain bears, like the Marines, they're they're they're tough, they don't let anything really in.
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But when they pick up that there's this now systemic inflammatory signal that's playing out, they shift into this huge defense state.
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So they start releasing their own inflammatory mediators, calling for backup, creating their own.
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recruiting.
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And that's, I think what's really interesting is the brain chemistry starts to go really sideways.
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And we have this, uh, like for example, we see that there's this particular enzyme that's been implicated with the neuroinflammation that arises with this process.
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And it's called IDO, endolamine two three dioxygenase.
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Yeah, yeah, of course.
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Showing 541–560 of 1,037 · page 28 of 52
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