Dr. Alok Kanojia (Dr. K)

And the whole point of treatment-resistant depression is that it is resistant to treatment.

So if I try to treat treatment-resistant depression, it doesn't work.

So there's a class of patients that I've absolutely worked with who have depression that doesn't seem to be treatable by things like antidepressant medication.

The really cool thing is that some of these psychedelic medications or some of these psychedelics seem to help the people who have difficulty benefiting from other sorts of treatments.

That's why it's really exciting.

So we're going to take another look at another table.

So this is a table that's looking at comparisons of the effects of psychedelics under different evaluation systems.

So now what we're doing, so I don't know if this kind of makes sense.

This graph, we're going to do Science 101, looking at a condition.

So for treatment-resistant depression, here's what psilocybin shows.

Here's what ayahuasca shows.

I think this graph, I think, is more important in some ways or better.

So now we're looking at, if we look at psilocybin, here's what we find for the antidepressant effect.

If we're looking at psilocybin, here's what we find for the anxiolytic effect.

Here's what we find for the suicide prevention effect.

And if we're looking at LSD, here's the antidepressant effect.

Here's the anxiolytic effect.

Right.

Here's ayahuasca.

Here's the antidepressant effect.