Dr. Ben Bikman

It was just, a paper was just published.

So you look at the degree of blindness that occurs in adults and those using the drug, it was more than twice the risk of developing blindness.

Now that's correlational.

We don't know what else they may be doing.

And so I don't mean to suggest that, I truly don't mean to suggest the drug is causing blindness.

No more than someone could say the drug is promoting longevity, although you actually can do a hard outcome with blindness.

You can't really do the hard outcome with when does the person die very well.

But there's so many variables that get worked in here that I cannot say it's because of the drug.

But it is worth another reason to have some caution that.

what's the point so maybe we just come back to the dose that maybe that's where we can find a common ground for all the enthusiasts and those who are enthusiastic but also a little skeptical on my end where i am enthusiastic but i also just want to bring in a note of caution maybe where we do have that common ground is the dose so with regards to glp-1 at the risk of seeing everything through a singular lens

One of the most common variables that predicts longevity within families, there's one paper that actually mentions the word of familial longevity.

And then the longevity studies like the Amores study in Sweden or the Honolulu aging study or the Shanghai aging study, some of the most consistent variables is longevity.

metabolic health, optimal glucose levels and insulin sensitivity.

In fact, that one study, I think it was in the Mediterranean that looked at families where you have a high number of centenarians.

They found that the most common theme was that they were all very insulin sensitive.

And as much as people have a – over the years, there's been an ideology of villainizing protein as a villain of aging because protein activates mTOR.

And when mTOR is too activated, it promotes aging.

I find that view unfortunate because –

for reasons you and I've mentioned, like muscle and bone mass, you have to have mTOR turned on.

You have to, or you can't have any anabolic, no retention of lean mass, let alone building it.