Dr. Ben Bikman

You know, glucagon, for example, insulin's opposite.

Muscle doesn't have glucagon receptors.

Like it's very much tissue specific, but insulin just operates at a different level.

And I'm glad to see that you're a, maybe you always have been, but you're converted.

You can see the value of insulin.

No, you, in fact, I love that you mentioned this.

So you are, most people may be, but you, I know you're familiar with Cynthia Kenyon's work where when I first heard about that kind of pathway, I, it was further justification of this insulin centric view.

Now, not to the extent, not that either of us, I am certainly not suggesting there aren't other variables.

Oxidative stress is a variable.

Stress is a variable, but there's one that I know, and the reason I focus on insulin so much is because of these kinds of results where you can just control one single variable and a simple one at that because insulin is a signal that we can control within 24 hours.

Like a person listening to this who's thinking, okay, I have all these signs and symptoms of insulin resistance.

What do I do?

Control your carbs.

That is the main signal.

Now, I'm not, again, I don't want to get off topic.

I'm not saying don't eat them, but just be smarter about what carbs you are eating and be a little, and then focus on these good sources of protein and fat, which aren't going to have an insulin spike.

That's why these other variables, people want to invoke the mitochondria.

I am extremely familiar with mitochondrial bioenergetics.

And yet, why don't I invoke the mitochondria as a primary source of disease?

Because you can't measure it in the average person.