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Dr. Casey Means

๐Ÿ‘ค Speaker
1139 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

It means promoting mitochondrial biogenesis.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

It means increasing the oxidative capacity of our individual mitochondria.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

It means improving mitochondrial fusion, which is actually when mitochondria come together to form long chains of mitochondria that are more efficient.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So there's a lot of technicality to what it means to print more mitochondria, have them each be more efficient, and have each one do more work.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But that's really what we want to do.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

That's when it just gets into the simple habits.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

There's simple things we can do for each of those things.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

For mitophagy, we can focus on various types of endurance exercise and high-intensity interval exercise.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

There's compounds like urolithin A that promote mitophagy.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

When we talk about improving our oxidative capacity, this is things like the sprint workouts.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

We want to build more mitochondria.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

This is resistance training.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Literally,

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

telling the body to make more.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But first principles, it's how do we get more of these working better, doing more work every day?

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And then we think about, you look at the data on walking, and it's like people who walk more than 7,000 steps a day have a 50% to 65% lower chance of dying in 10-year follow-ups.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And it's like, yeah, because walking is literally

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

glucose disposal signal so you're just simply asking it's not a great biogenesis signal it's not a great mitophagy signal but it's a great disposal so if you're doing lifestyle habits that do one of those three things which we can of course go into more you're improving the cells capacity to do that conversion process better

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

I would say at least three.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

I would say aiming for more than that is good, though.