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Dr. Chris Palmer

๐Ÿ‘ค Person
1446 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

And that when researchers take these mitochondria and like mess them up or something, the cell doesn't develop normally. You know, they've been implicated in all of the phases of the human stress response to psychological stress. So that includes cortisol release, noradrenaline release, It includes inflammation and it includes epigenetic changes.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

And that when researchers take these mitochondria and like mess them up or something, the cell doesn't develop normally. You know, they've been implicated in all of the phases of the human stress response to psychological stress. So that includes cortisol release, noradrenaline release, It includes inflammation and it includes epigenetic changes.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

And that when researchers take these mitochondria and like mess them up or something, the cell doesn't develop normally. You know, they've been implicated in all of the phases of the human stress response to psychological stress. So that includes cortisol release, noradrenaline release, It includes inflammation and it includes epigenetic changes.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So those are kind of the four buckets of the human stress response. Cortisol. adrenaline, inflammation, and epigenetic changes. And researchers actually manipulated mitochondrial genes, two genes in the cell nucleus that control for mitochondrial proteins and two genes in mitochondria themselves. And by manipulating these four different genes, one at a time in mice,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So those are kind of the four buckets of the human stress response. Cortisol. adrenaline, inflammation, and epigenetic changes. And researchers actually manipulated mitochondrial genes, two genes in the cell nucleus that control for mitochondrial proteins and two genes in mitochondria themselves. And by manipulating these four different genes, one at a time in mice,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So those are kind of the four buckets of the human stress response. Cortisol. adrenaline, inflammation, and epigenetic changes. And researchers actually manipulated mitochondrial genes, two genes in the cell nucleus that control for mitochondrial proteins and two genes in mitochondria themselves. And by manipulating these four different genes, one at a time in mice,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

they could impact all of the four aspects of the stress response. And so what that means is that mitochondria are somehow involved in regulating the human stress response. And so the way that I think about it is that, and the way that many researchers actually think about it now is is that mitochondria, you know, there are hundreds, sometimes thousands of them in our cells, in each of our cells.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

they could impact all of the four aspects of the stress response. And so what that means is that mitochondria are somehow involved in regulating the human stress response. And so the way that I think about it is that, and the way that many researchers actually think about it now is is that mitochondria, you know, there are hundreds, sometimes thousands of them in our cells, in each of our cells.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

they could impact all of the four aspects of the stress response. And so what that means is that mitochondria are somehow involved in regulating the human stress response. And so the way that I think about it is that, and the way that many researchers actually think about it now is is that mitochondria, you know, there are hundreds, sometimes thousands of them in our cells, in each of our cells.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

Most neurons have thousands of mitochondria. The mitochondria are actually moving around. They use the cytoskeleton to move around the cell. They fuse with each other. They It's called mitochondrial dynamics. They like change shape. They do all sorts of things. And again, that impacts all of these signaling processes. But that's just within one little cell.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

Most neurons have thousands of mitochondria. The mitochondria are actually moving around. They use the cytoskeleton to move around the cell. They fuse with each other. They It's called mitochondrial dynamics. They like change shape. They do all sorts of things. And again, that impacts all of these signaling processes. But that's just within one little cell.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

Most neurons have thousands of mitochondria. The mitochondria are actually moving around. They use the cytoskeleton to move around the cell. They fuse with each other. They It's called mitochondrial dynamics. They like change shape. They do all sorts of things. And again, that impacts all of these signaling processes. But that's just within one little cell.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So you can think of one cell as like almost a village of mitochondria that they're all just doing different things and working together to help that cell function. But in fact, when you think about hormones like cortisol,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So you can think of one cell as like almost a village of mitochondria that they're all just doing different things and working together to help that cell function. But in fact, when you think about hormones like cortisol,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

So you can think of one cell as like almost a village of mitochondria that they're all just doing different things and working together to help that cell function. But in fact, when you think about hormones like cortisol,

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

You can think about it as a way for mitochondria in one cell to produce cortisol, that they can get sent to mitochondria in another cell to make that other cell do something, to either increase its activity or decrease its activity. Some people actually think about human cells as just a network of mitochondria, right?

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

You can think about it as a way for mitochondria in one cell to produce cortisol, that they can get sent to mitochondria in another cell to make that other cell do something, to either increase its activity or decrease its activity. Some people actually think about human cells as just a network of mitochondria, right?

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

You can think about it as a way for mitochondria in one cell to produce cortisol, that they can get sent to mitochondria in another cell to make that other cell do something, to either increase its activity or decrease its activity. Some people actually think about human cells as just a network of mitochondria, right?

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

All kind of mitochondria throughout the body and brain are just doing all sorts of things. And at the end of the day, we come back to just common sense. At the end of the day, it's about helping the organism adapt and survive. Ultimately, organisms, rule number one, they need to survive. Rule number two, they need to reproduce. And rule number three, they need to adapt.

Huberman Lab
Transform Your Mental Health With Diet & Lifestyle | Dr. Chris Palmer

All kind of mitochondria throughout the body and brain are just doing all sorts of things. And at the end of the day, we come back to just common sense. At the end of the day, it's about helping the organism adapt and survive. Ultimately, organisms, rule number one, they need to survive. Rule number two, they need to reproduce. And rule number three, they need to adapt.