Dr. David Agus
👤 PersonAppearances Over Time
Podcast Appearances
What we just learned from AI was that the shingles vaccine, which is a vaccine to prevent shingles that we classically do in our country after age 50, looks like it may reduce Alzheimer's by almost 50%. Pretty powerful observation.
What we just learned from AI was that the shingles vaccine, which is a vaccine to prevent shingles that we classically do in our country after age 50, looks like it may reduce Alzheimer's by almost 50%. Pretty powerful observation.
What we just learned from AI was that the shingles vaccine, which is a vaccine to prevent shingles that we classically do in our country after age 50, looks like it may reduce Alzheimer's by almost 50%. Pretty powerful observation.
You know, very simply is that our goal today, every single person on this planet wants to live better, longer, healthier. The way we could take shortcuts is learning from other species. We've all been on the earth a million years, us and the other species. There are things they've adapted to in ways they've done it to hack their own system that we can learn from and benefit to ours.
You know, very simply is that our goal today, every single person on this planet wants to live better, longer, healthier. The way we could take shortcuts is learning from other species. We've all been on the earth a million years, us and the other species. There are things they've adapted to in ways they've done it to hack their own system that we can learn from and benefit to ours.
You know, very simply is that our goal today, every single person on this planet wants to live better, longer, healthier. The way we could take shortcuts is learning from other species. We've all been on the earth a million years, us and the other species. There are things they've adapted to in ways they've done it to hack their own system that we can learn from and benefit to ours.
So I'm walking with my family on a safari in Africa, coolest trip ever. And an elephant walks by and I say to the guide, hey, they must get lots of cancer. They're 40 to 50 times bigger than us, 40 to 50 times more cells. They're in the sun all day. And he looks at me and say, elephants don't get cancer. And when you look, elephants have 20 copies of a gene called P53, the guardian of the genome.
So I'm walking with my family on a safari in Africa, coolest trip ever. And an elephant walks by and I say to the guide, hey, they must get lots of cancer. They're 40 to 50 times bigger than us, 40 to 50 times more cells. They're in the sun all day. And he looks at me and say, elephants don't get cancer. And when you look, elephants have 20 copies of a gene called P53, the guardian of the genome.
So I'm walking with my family on a safari in Africa, coolest trip ever. And an elephant walks by and I say to the guide, hey, they must get lots of cancer. They're 40 to 50 times bigger than us, 40 to 50 times more cells. They're in the sun all day. And he looks at me and say, elephants don't get cancer. And when you look, elephants have 20 copies of a gene called P53, the guardian of the genome.
We have one copy. And what that gene does is it corrects error in DNA from inflammation. So here's a remarkable clue for us. First of all, we can recapitulate that. We can prevent all cancer. But in the short run, we have to take ways to downregulate inflammation. Elephants never get cancer? Elephants rarely get cancer.
We have one copy. And what that gene does is it corrects error in DNA from inflammation. So here's a remarkable clue for us. First of all, we can recapitulate that. We can prevent all cancer. But in the short run, we have to take ways to downregulate inflammation. Elephants never get cancer? Elephants rarely get cancer.
We have one copy. And what that gene does is it corrects error in DNA from inflammation. So here's a remarkable clue for us. First of all, we can recapitulate that. We can prevent all cancer. But in the short run, we have to take ways to downregulate inflammation. Elephants never get cancer? Elephants rarely get cancer.
So you would think that with so many cells and so many divisions, they have much more cancer than us and they don't. And it's really interesting. Part of the reason is, is that, you know, we have children in their 20s and 30s. And then actually evolution said, I don't care about you because I care about who has good kids. In fact, if you die of cancer, heart disease, etc.,
So you would think that with so many cells and so many divisions, they have much more cancer than us and they don't. And it's really interesting. Part of the reason is, is that, you know, we have children in their 20s and 30s. And then actually evolution said, I don't care about you because I care about who has good kids. In fact, if you die of cancer, heart disease, etc.,
So you would think that with so many cells and so many divisions, they have much more cancer than us and they don't. And it's really interesting. Part of the reason is, is that, you know, we have children in their 20s and 30s. And then actually evolution said, I don't care about you because I care about who has good kids. In fact, if you die of cancer, heart disease, etc.,
It brings more food and housing to the next generation. Well, elephant females give birth until their sixth decade. Dominant males protect the herd until the day they die. And so they couldn't afford to get cancer. And we can't, right? Cancer rarely happens in kids, but it happens as we enter our later years. And here's a way that we could potentially prevent it.
It brings more food and housing to the next generation. Well, elephant females give birth until their sixth decade. Dominant males protect the herd until the day they die. And so they couldn't afford to get cancer. And we can't, right? Cancer rarely happens in kids, but it happens as we enter our later years. And here's a way that we could potentially prevent it.
It brings more food and housing to the next generation. Well, elephant females give birth until their sixth decade. Dominant males protect the herd until the day they die. And so they couldn't afford to get cancer. And we can't, right? Cancer rarely happens in kids, but it happens as we enter our later years. And here's a way that we could potentially prevent it.
Well, first is you do all the research about P53 and that's ongoing. But today we say, hey, listen, what it's doing is correcting errors in DNA that came about from inflammation. So how can we downregulate inflammation in our lives today? Well, there's a simple way, the class of drugs called statins. That's the Lipitor, the cresters of the world.
Well, first is you do all the research about P53 and that's ongoing. But today we say, hey, listen, what it's doing is correcting errors in DNA that came about from inflammation. So how can we downregulate inflammation in our lives today? Well, there's a simple way, the class of drugs called statins. That's the Lipitor, the cresters of the world.