Dr. David Agus

Well, first is you do all the research about P53 and that's ongoing. But today we say, hey, listen, what it's doing is correcting errors in DNA that came about from inflammation. So how can we downregulate inflammation in our lives today? Well, there's a simple way, the class of drugs called statins. That's the Lipitor, the cresters of the world.

While they do lower cholesterol, the real mechanism is downmodulating inflammation. And if you look at the studies, it actually reduces cancer. And then you look for sources of inflammation in your life and you want to avoid them. And so it sounds simple. It's actually more complex, but it's doable today. You know, take another crazy example. Do you have a dog? Yeah, I do.

While they do lower cholesterol, the real mechanism is downmodulating inflammation. And if you look at the studies, it actually reduces cancer. And then you look for sources of inflammation in your life and you want to avoid them. And so it sounds simple. It's actually more complex, but it's doable today. You know, take another crazy example. Do you have a dog? Yeah, I do.

While they do lower cholesterol, the real mechanism is downmodulating inflammation. And if you look at the studies, it actually reduces cancer. And then you look for sources of inflammation in your life and you want to avoid them. And so it sounds simple. It's actually more complex, but it's doable today. You know, take another crazy example. Do you have a dog? Yeah, I do.

Your dog sleeps all day. And the reason is your dog doesn't get deep sleep. If it got deep sleep, you could walk right by it and do something to the herd or whatever they were bred to protect. Your first night in a hotel, you sleep like a dog because you don't recognize the surroundings.

Your dog sleeps all day. And the reason is your dog doesn't get deep sleep. If it got deep sleep, you could walk right by it and do something to the herd or whatever they were bred to protect. Your first night in a hotel, you sleep like a dog because you don't recognize the surroundings.

Your dog sleeps all day. And the reason is your dog doesn't get deep sleep. If it got deep sleep, you could walk right by it and do something to the herd or whatever they were bred to protect. Your first night in a hotel, you sleep like a dog because you don't recognize the surroundings.

And you go, oh, my gosh, your body says, hey, I don't want to have deep sleep because I don't recognize the surroundings. And it's dangerous. Something could happen to me. So when I travel, I bring my pillowcase from home. So I have my sensory, my smell and my feel from home. I use my iPhone as my clock from home. So I have a visual cue also, and I get more deep sleep.

And you go, oh, my gosh, your body says, hey, I don't want to have deep sleep because I don't recognize the surroundings. And it's dangerous. Something could happen to me. So when I travel, I bring my pillowcase from home. So I have my sensory, my smell and my feel from home. I use my iPhone as my clock from home. So I have a visual cue also, and I get more deep sleep.

And you go, oh, my gosh, your body says, hey, I don't want to have deep sleep because I don't recognize the surroundings. And it's dangerous. Something could happen to me. So when I travel, I bring my pillowcase from home. So I have my sensory, my smell and my feel from home. I use my iPhone as my clock from home. So I have a visual cue also, and I get more deep sleep.

So I've kind of learned from the dog how to do the opposite in a sense when I travel, because I don't want to sleep like a dog when I go to a hotel.

So I've kind of learned from the dog how to do the opposite in a sense when I travel, because I don't want to sleep like a dog when I go to a hotel.

So I've kind of learned from the dog how to do the opposite in a sense when I travel, because I don't want to sleep like a dog when I go to a hotel.

Well, there was an amazing study in Europe, in the UK, where they actually took a talent and they took everybody and they divided them in half. They did no blood draws and they put them on a baby aspirin and a statin, two ways to downregulate inflammation.

Well, there was an amazing study in Europe, in the UK, where they actually took a talent and they took everybody and they divided them in half. They did no blood draws and they put them on a baby aspirin and a statin, two ways to downregulate inflammation.

Well, there was an amazing study in Europe, in the UK, where they actually took a talent and they took everybody and they divided them in half. They did no blood draws and they put them on a baby aspirin and a statin, two ways to downregulate inflammation.

And what they showed is the people on placebo who got a pill, they didn't know what it was, lived shorter than the people on the statin and the aspirin who lived much longer. So all of a sudden there's real data there. You know, we're in health. If I tell you to go on a pill where you're not going to feel differently and it's going to help you in 10 or 20 years, you roll your eyes at me.

And what they showed is the people on placebo who got a pill, they didn't know what it was, lived shorter than the people on the statin and the aspirin who lived much longer. So all of a sudden there's real data there. You know, we're in health. If I tell you to go on a pill where you're not going to feel differently and it's going to help you in 10 or 20 years, you roll your eyes at me.

And what they showed is the people on placebo who got a pill, they didn't know what it was, lived shorter than the people on the statin and the aspirin who lived much longer. So all of a sudden there's real data there. You know, we're in health. If I tell you to go on a pill where you're not going to feel differently and it's going to help you in 10 or 20 years, you roll your eyes at me.

We don't have a near-term readout. And so it's been very difficult to get compliance and to get people to do them. There's a new generation of statin equivalents, drugs that lower inflammation and cholesterol that came out that literally are a shot once a year. It's a technology called siRNA. They're FDA approved, and they could downregulate the pathways to lower cholesterol a year at a time.