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Dr. David Fajgenbaum

๐Ÿ‘ค Speaker
1737 total appearances

Appearances Over Time

Podcast Appearances

Radiolab
The Medical Matchmaking Machine

Maybe we can find something else for angiosarcoma.

Radiolab
The Medical Matchmaking Machine

And that's when we came across a study that had been published.

Radiolab
The Medical Matchmaking Machine

I'm so annoying to them.

Radiolab
The Medical Matchmaking Machine

They're like, they're looking at me and they're like, your uncle has a terminal illness.

Radiolab
The Medical Matchmaking Machine

The last thing he needs is for his nephew to tell him or me that there's a treatment out there that can help him.

Radiolab
The Medical Matchmaking Machine

Like, that's not what he needs right now is what they're thinking.

Radiolab
The Medical Matchmaking Machine

And in my mind, I'm like, are you kidding me?

Radiolab
The Medical Matchmaking Machine

He's still here.

Radiolab
The Medical Matchmaking Machine

He's still breathing.

Radiolab
The Medical Matchmaking Machine

I just walked past a CVS.

Radiolab
The Medical Matchmaking Machine

And last time I checked, there's 4,000 drugs in that CVS.

Radiolab
The Medical Matchmaking Machine

And I know those 4,000 drugs haven't been tried for him.

Radiolab
The Medical Matchmaking Machine

So until we tried all 4,000 drugs, you can't tell me there isn't a drug in there that can help him.

Radiolab
The Medical Matchmaking Machine

And so we find a study that had been published three years earlier that basically says that four out of five people with my uncle's cancer have very high expression of something called PD-L1.

Radiolab
The Medical Matchmaking Machine

I'm here saying like, let's test this tumor for PD-L1.

Radiolab
The Medical Matchmaking Machine

And the doctor says, I'm not going to test it because no one with angiosarcoma has ever been given a PD-1 inhibitor.

Radiolab
The Medical Matchmaking Machine

I think there's like a...

Radiolab
The Medical Matchmaking Machine

less than 10% chance that this gene panel that you want to order for Michael is going to come out with anything helpful.

Radiolab
The Medical Matchmaking Machine

And I hear less than 10%.

Radiolab
The Medical Matchmaking Machine

And I'm like, that's great.