Dr. David Sinclair
π€ SpeakerAppearances Over Time
Podcast Appearances
This is a new finding out of Spain.
Manuel Serrano's lab has found that
excess iron will increase the number of senescent cells in the body.
And senescent cells are these zombie cells that accumulate as you get older and they sit there and they cause inflammation mainly and also can cause cancer.
And it's found that if you get rid of these cells or never accumulate them, you stay younger.
In animals, and there's a
some really interesting studies out of Mayo Clinic in humans as well.
And what I find, for example, is people who are really healthy and live the way I do and have a diet that's fairly vegetarian, but not strict, still have slightly low hemoglobin levels, slightly low iron, slightly low ferritin, but we have super amounts of energy.
We're not anemic.
And we're getting along great in life.
But a doctor who just looks at that might say, oh, we need to give you more iron.
So what I'm getting at is an example of we need to personalize medicine and look at people over the long run to know what works for them and what's healthy for them.
And not just work towards the average human, but work towards what's optimal for human.
Yeah.
The first is that you should be tracking things because one measurement isn't enough.
These things vary and over time.
And if you can have a decade or more of data, it's super informative, as you know.
But there are some main ones.
I would say your blood sugar levels, you want to do your HbA1c, which is your average glucose levels over the month.
There's CRP, which I mentioned for inflammation.