Dr. Frances Arnold

speaker
245 appearances 1 recordings 1 series first heard Aug 2026 last heard 3 Aug

Dr. Frances Arnold’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.

Appearances

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Say an enzyme that catalyzes a whole new chemical reaction may become possible when you go out into these new spaces.
But you have to know what you're looking for.
And sometimes all those new properties would be lost because you have no way of knowing that they're there.
Yes, if you know what you're looking for.
It's not going to raise its hand and say, oh, I can build a new carbon-silicon bond.
I may not take off stains, but I can do this.
No, it's not going to tell you that.
You have to ask it a million questions.
Well, I mean, we're searching an almost infinite space, and you can't search infinite questions against an infinite space.
Humans can't do that.
But, you know, biology does it.
Novelty happens because all of this incredible diversity of the biological world is constantly changing and constantly looking for new opportunities for survival, right?
Survival of the fittest.
So a new solution to, let's say, eating up an environmental pollutant can just pop up anywhere in the world.
That's so incredible because it gives, if you say, for example, you break down an environmental pollutant and it gives you a new rich nitrogen source, you have a selective advantage over your neighbors and you grow faster and then you can occupy the whole world to eat up that pollutant.
I don't have any way to do that when I'm breeding in the laboratory.
All of that, yes.
So we have a great big refrigerator of things that we've made that are now no longer what you would find in the natural world.
We have an even bigger database of enzymes that all of science has deposited.
what we understand.
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