Dr Jay Jagannathan
speaker
177 appearances
1 recordings
1 series
first heard Apr 2026
last heard 30 Apr
Dr Jay Jagannathan’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Apr 2026 with 1.
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There are changes in proportions of areas, such as gray matter and white matter, that happen as we get older as well.
And there are effects of hormones, such as estrogen, on those factors I'm sure we'll discuss in this podcast as well.
And even aside from the structure, there are areas in the brain, such as fluid spaces, the ventricles, things like that, that change in terms of size and in terms of compliance as we get older.
And all those have significant impacts in terms of cognitive function and in terms of behavior and other things.
Yeah, exactly.
You know, I mean, every part of the brain obviously has an extremely valuable role.
I mean, the frontal lobe is the area that kind of controls, you know, impulsivity, you know, the cognitive thinking, what we think about personality, stuff like that.
You know, there are areas of the brain, such as the temporal lobe, that controls more language, more spatial orientation, things like that.
brain stem, which controls critical functions such as breathing, things that we don't even know that we're doing, but are absolutely critical for life.
Other important connection is that within these parts of the brain, there are different types of neurotransmitters.
Neurotransmitters are the chemicals, almost the currency that the brain uses to communicate with different parts.
And these parts play significant roles in the overall internal milieu of the brain, as well as in communication with external hormones within the brain itself.
And that also plays a role, and those shifts also play a role in terms of how our brain develop over the course of both in our youth and as we get older.
Now, the one thing that is true when we are very young is the brain's capability of remodeling is a lot more rapid.
So you have something called plasticity, which is the ability of these premature cells to really be able to remodel.
We don't fully understand that, obviously, but certain areas of the brain, the hippocampus,
The occipital lobe are able to rapidly model.
For example, in a child with a brain tumor, I'll never forget from my training, we took out a tumor in the occipital lobe of a child that encompassed basically the whole occipital lobe.
And in an adult, if you had taken that out, the patient would have been blinded for life.
But this child had it in infancy.
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