Dr. Jen Gunter

So you can't say, well, if Premarin does this, then estradiol will do this.

You have to study it for estradiol.

And it was only the Premarin alone arm that did that.

So meaning people who didn't get a progestin, which was in the study.

And so people cherry pick.

So it's like, well, wait a minute.

If you think the WHI is the worst study ever, then why are you choosing some data from it?

to support your conclusions and then ignoring others.

So the best compilation of all of the data, because there's all kinds of observational studies, there's prospective studies, all kinds of things, I think comes from both the Menopause Society and also the Australasian Menopause Society has fantastic stuff on their website.

Those are the two that I personally

feel have condensed the information.

And the Australasian Menopause Society have some actually great patient handouts, but they also have some forms of medications that aren't available here.

So yeah, I kind of put that in context.

But for many people, so I actually keep printouts of the 2022

menopause society guidelines for hormone therapy in my office.

And at the end of each segment, there really is kind of a nice summary about, you know, there's all the, you know, this is observational, this isn't, if you take out the unblinded studies, blah, blah, blah, which is, I find really fascinating, but obviously a lot of people don't hear that.

they it's all clear it really they've they've sifted through the data they they have all declared their biases you know when you you and i know getting a whole bunch of doctors in a room to agree to something and they also have neuroscientists involved like getting people to agree to something is not easy people like well what about this anyway you know people have their you know their pet projects and all this kind of stuff and so when you have that kind of consensus it's a really great launching point and i think that

that when people speak against the guidelines, they do a huge disservice to all of the people who have dedicated their lives to studying this, right?

Some of the giants of menopause have collected those guidelines and put that together.

And one thing that I hear a lot from internet influencers is that, oh, the guidelines are out of date.