Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

Dr. John Kruse

๐Ÿ‘ค Speaker
915 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

They're the same active ingredients as far as we can tell. And when it got approval in the U.S., it was approved for narcolepsy, where people are falling abruptly asleep during the day, so it keeps them alert and awake there. It also got approval for circadian sleep shift work disorder, where because you're on a shift schedule, you're sleeping weirdly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

They're the same active ingredients as far as we can tell. And when it got approval in the U.S., it was approved for narcolepsy, where people are falling abruptly asleep during the day, so it keeps them alert and awake there. It also got approval for circadian sleep shift work disorder, where because you're on a shift schedule, you're sleeping weirdly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

They're the same active ingredients as far as we can tell. And when it got approval in the U.S., it was approved for narcolepsy, where people are falling abruptly asleep during the day, so it keeps them alert and awake there. It also got approval for circadian sleep shift work disorder, where because you're on a shift schedule, you're sleeping weirdly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And it got approval for daytime sleepiness from sleep apnea. But even at that time when it was approved, there were dozens of studies that showed, regardless of why you're sleepy, whether it was sedating medication, whether you had lupus or MS, whether you had some other condition, it works pretty well for keeping people alert and awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And it got approval for daytime sleepiness from sleep apnea. But even at that time when it was approved, there were dozens of studies that showed, regardless of why you're sleepy, whether it was sedating medication, whether you had lupus or MS, whether you had some other condition, it works pretty well for keeping people alert and awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And it got approval for daytime sleepiness from sleep apnea. But even at that time when it was approved, there were dozens of studies that showed, regardless of why you're sleepy, whether it was sedating medication, whether you had lupus or MS, whether you had some other condition, it works pretty well for keeping people alert and awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So more than keeping alert and awake, there does seem to be evidence that it helps with some of the executive functions of attention, concentration. My clinical experience with it, it tends to be, again, with the amphetamine on top, Many fewer people describe it as being helpful or as helpful.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So more than keeping alert and awake, there does seem to be evidence that it helps with some of the executive functions of attention, concentration. My clinical experience with it, it tends to be, again, with the amphetamine on top, Many fewer people describe it as being helpful or as helpful.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So more than keeping alert and awake, there does seem to be evidence that it helps with some of the executive functions of attention, concentration. My clinical experience with it, it tends to be, again, with the amphetamine on top, Many fewer people describe it as being helpful or as helpful.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

On the other hand, there's one study, and I'm forgetting the principal investigators, it was at Brown University, where they used some very clever, sophisticated approach to try to sort out motivation versus pure cognitive functioning. And their claim, and it was a very well done study, they were comparing it directly to an amphetamine product. Their claim

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

On the other hand, there's one study, and I'm forgetting the principal investigators, it was at Brown University, where they used some very clever, sophisticated approach to try to sort out motivation versus pure cognitive functioning. And their claim, and it was a very well done study, they were comparing it directly to an amphetamine product. Their claim

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

On the other hand, there's one study, and I'm forgetting the principal investigators, it was at Brown University, where they used some very clever, sophisticated approach to try to sort out motivation versus pure cognitive functioning. And their claim, and it was a very well done study, they were comparing it directly to an amphetamine product. Their claim

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

was that modafinil was the one that was actually boosting cognitive functions and not just boosting motivation, whereas that most of... amphetamines benefit for ADHD. When we say it helps me concentrate, it helps me sustain focus, it makes me less distracted, their feeling, their analysis was that stimulant was mostly working on motivation.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

was that modafinil was the one that was actually boosting cognitive functions and not just boosting motivation, whereas that most of... amphetamines benefit for ADHD. When we say it helps me concentrate, it helps me sustain focus, it makes me less distracted, their feeling, their analysis was that stimulant was mostly working on motivation.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

was that modafinil was the one that was actually boosting cognitive functions and not just boosting motivation, whereas that most of... amphetamines benefit for ADHD. When we say it helps me concentrate, it helps me sustain focus, it makes me less distracted, their feeling, their analysis was that stimulant was mostly working on motivation.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

It's a controlled substance, but not nearly, not the same schedule as amphetamine and Ritalin. So it's easier for some prescribers to prescribe.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

It's a controlled substance, but not nearly, not the same schedule as amphetamine and Ritalin. So it's easier for some prescribers to prescribe.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

It's a controlled substance, but not nearly, not the same schedule as amphetamine and Ritalin. So it's easier for some prescribers to prescribe.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Even though it's the non-stimulant stimulant, and I'd say most people do experience, you know, I feel more alert or awake or better, but I don't feel revved up, about 10% to 15% of people that I've worked with and others have written about it, so I don't think it's unique, will feel revved up when they take it the first few times.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Even though it's the non-stimulant stimulant, and I'd say most people do experience, you know, I feel more alert or awake or better, but I don't feel revved up, about 10% to 15% of people that I've worked with and others have written about it, so I don't think it's unique, will feel revved up when they take it the first few times.