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Dr. John Kruse

๐Ÿ‘ค Speaker
915 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

The potential downside is again that the capacity of the red blood cells is limited so at some point For most people, because that's a rate-limiting step, when you're adding more and more, you're actually extending the duration of time more than you're getting a bigger peak because your red blood cells just aren't cleaving it fast enough to make more dextroamphetamine available.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

The potential downside is again that the capacity of the red blood cells is limited so at some point For most people, because that's a rate-limiting step, when you're adding more and more, you're actually extending the duration of time more than you're getting a bigger peak because your red blood cells just aren't cleaving it fast enough to make more dextroamphetamine available.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Almost invariably when I'll ask, you know, how did this compare to your Adderall XR or to a Hansi, they'll say smooth. Smooth. They're getting it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Almost invariably when I'll ask, you know, how did this compare to your Adderall XR or to a Hansi, they'll say smooth. Smooth. They're getting it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Almost invariably when I'll ask, you know, how did this compare to your Adderall XR or to a Hansi, they'll say smooth. Smooth. They're getting it.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Good question. So I'd say there's two different angles. And I think, I mean, the one that's easier to objectively measure is putting people in a lab and there's a simple test, a time perception test, and you interrupt them after a certain period. I mean, say you're going to be estimating how long you're left without interruption. And People with ADHD, they're inconsistently inconsistent.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Good question. So I'd say there's two different angles. And I think, I mean, the one that's easier to objectively measure is putting people in a lab and there's a simple test, a time perception test, and you interrupt them after a certain period. I mean, say you're going to be estimating how long you're left without interruption. And People with ADHD, they're inconsistently inconsistent.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Good question. So I'd say there's two different angles. And I think, I mean, the one that's easier to objectively measure is putting people in a lab and there's a simple test, a time perception test, and you interrupt them after a certain period. I mean, say you're going to be estimating how long you're left without interruption. And People with ADHD, they're inconsistently inconsistent.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Consistently inconsistent. So it's not that they perpetually underestimate or overestimate, but they are estimating incorrectly much more often than people without ADHD. So there's something at a basic time processing level that's aberrant there.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Consistently inconsistent. So it's not that they perpetually underestimate or overestimate, but they are estimating incorrectly much more often than people without ADHD. So there's something at a basic time processing level that's aberrant there.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

Consistently inconsistent. So it's not that they perpetually underestimate or overestimate, but they are estimating incorrectly much more often than people without ADHD. So there's something at a basic time processing level that's aberrant there.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But there's also getting, you know, the real world aspect of not paying attention to cues or not noticing other people left the room or not being distracted, which compounds the situation. And I mean, it's also interesting to the extent to which many people aren't. So I often ask, even though it's not one of the 18 symptoms, are you chronically late?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But there's also getting, you know, the real world aspect of not paying attention to cues or not noticing other people left the room or not being distracted, which compounds the situation. And I mean, it's also interesting to the extent to which many people aren't. So I often ask, even though it's not one of the 18 symptoms, are you chronically late?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But there's also getting, you know, the real world aspect of not paying attention to cues or not noticing other people left the room or not being distracted, which compounds the situation. And I mean, it's also interesting to the extent to which many people aren't. So I often ask, even though it's not one of the 18 symptoms, are you chronically late?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And particularly people who show up late to my office time after time. So one of my favorite quotes is, this person who the session before we had been talking that her boss was giving her threatening notices because she had come in two hours late one day and she had all sorts of good excuses of why she couldn't get out the door. And we were talking, you know, are you regularly late? No, no, no.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And particularly people who show up late to my office time after time. So one of my favorite quotes is, this person who the session before we had been talking that her boss was giving her threatening notices because she had come in two hours late one day and she had all sorts of good excuses of why she couldn't get out the door. And we were talking, you know, are you regularly late? No, no, no.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And particularly people who show up late to my office time after time. So one of my favorite quotes is, this person who the session before we had been talking that her boss was giving her threatening notices because she had come in two hours late one day and she had all sorts of good excuses of why she couldn't get out the door. And we were talking, you know, are you regularly late? No, no, no.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And I said, well, why was the boss so upset? And then I asked, well, when is the expectation? This was pre-COVID, pre-working. When is the expectation you're there? When do you usually show up? Oh, well, office starts at 9, and I'm usually there by 9.15, 9.20. That's not late. In her mind, it wasn't late. So when you ask a question, are you routinely late?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And I said, well, why was the boss so upset? And then I asked, well, when is the expectation? This was pre-COVID, pre-working. When is the expectation you're there? When do you usually show up? Oh, well, office starts at 9, and I'm usually there by 9.15, 9.20. That's not late. In her mind, it wasn't late. So when you ask a question, are you routinely late?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

And I said, well, why was the boss so upset? And then I asked, well, when is the expectation? This was pre-COVID, pre-working. When is the expectation you're there? When do you usually show up? Oh, well, office starts at 9, and I'm usually there by 9.15, 9.20. That's not late. In her mind, it wasn't late. So when you ask a question, are you routinely late?