Dr. Julia Nardi-Riddle

speaker
100 appearances 1 recordings 1 series first heard Aug 2026 last heard 6 Aug

Dr. Julia Nardi-Riddle’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.

Appearances

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So like a mania.
you know low in a bad depression or in this mixed state which is actually very hard to describe unique to postpartum depression is that it has a pretty rapid onset so we see it occur very very early in the postpartum often in the first few weeks but the truth of the experience of women is because it's so hard to diagnose and currently often gets missed it can have this very long tail where women really don't recover because they don't get the appropriate recognition and treatment
You know, some of the data has shown that if we can identify it early, right, either it's someone that had it in the past or they are lucky enough to be in care or have someone in their life that says, you are not yourself, let's get you to the hospital, and it is identified correctly.
Generally, with appropriate treatment, so we're talking early on, what you want to try to do is get that person sleeping.
So we're talking about like a benzodiazepine, maybe an antipsychotic, and then lithium.
Some data has shown within 40 days, we can really get that person back in, but usually they have to be hospitalized.
Now, the research also shows that in at least 50% of cases, it's misdiagnosed, which often means the wrong medicine is given.
So women can suffer with this for months and months, or it can mutate into something else.
So it's not that the natural course of it, it'll just go away.
We don't know enough about what happens if you hopefully get someone sleeping, but then do they have this long tail of a depression afterwards?
We don't have perfect data on that because we don't know who we're not seeing always.
The postpartum is like no other time in a human's life.
So many things change.
First and foremost, as a society, we don't fully understand how the brain works.
And the postpartum involves a few different things, right?
So in pregnancy, hormones go to levels not seen in any other time in our lives.
So estrogen, progesterone.
So the leading theory right now is...
As those drop off, which they drop off rapidly as a woman delivers a baby, it seems to be that there's a subset of women who are very susceptible to that change.
It's not a deficit, but it seems to be that either due to the neuroprotective agents within estrogen, due to substrates of progesterone, that parts of their brain do not respond to that rapid change the way somebody else that doesn't experience that does.
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