Dr. Karan Rajan
speaker
2,915 appearances
16 recordings
1 series
first heard May 2026
last heard 6d ago
Dr. Karan Rajan’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 16 in all, peaking in Jun 2026 with 5.
Appearances
I guess endometriosis is somewhat similar, where actually there's unique fingerprints of endometriosis.
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How important was that study to kind of progress
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that conversation and how useful is it to kind of tell us more of what we actually need to know?
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I also like recently, given that we know that there's this, you know, immune inflammatory component to endometriosis, I've seen a lot of people online with endometriosis and even some physicians discuss like, you know, this anecdotal data that they're seeing in their patient population and patients themselves reporting improvements in endosymptoms whilst being on a GLP one.
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And I wonder if you've seen that similar.
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overlap as well.
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And why do you think that is?
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Do you think that's because of the anti-inflammatory effects of GLP1s, independent of weight loss?
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And do you also feel that for patients with endometriosis who
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also have higher adiposity, some degree of weight loss may then improve the body composition and then improve endosymptoms to some degree.
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Like what do you think is going on there to cause this kind of symptomatology improvement with GLP ones?
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Another thing which may tie into the inflammation, also the immune system, which kind of underpins those as well as hormones, is the microbiome.
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I feel endometriosis and the microbiome is a bit of a black box.
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And for example, if you search endometriosis and microbiome on PubMed, you know, a repository of, you know, if anyone doesn't know what PubMed is, a repository of millions of, you know, scientific journals.
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If you type in
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Endometriosis and microbiome as a search term and then filter by clinical trials.
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I think you get about three clinical trials, and I think one of them may be relevant, but they're slightly underpowered.
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And yeah, even otherwise, just three clinical trials is kind of mind-blowing that there isn't more data on there.
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How important do you think the overlap is between the microbiome and endometriosis?
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And have you seen any
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Showing 1421–1440 of 2,915 · page 72 of 146
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