Dr. Kent Berridge
speaker
525 appearances
1 recordings
1 series
first heard Aug 2026
last heard 4 Aug
Dr. Kent Berridge’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.
Appearances
That's right.
There's no wanting for food if you're full.
Now, you can still have other wants because the society for food isn't going to suppress wanting for other things.
Sensitization is a more permanent kind of hunger-like state that can last in a person.
So that's why years later, even in a rat, if you sensitize them and then you don't give them drugs for a year, you come back a year later, they're still sensitized.
That's half a lifetime for a rat because they only live for two years.
Same thing if you take a person and they haven't taken drugs.
Again, Marco Leighton in Montreal has done this.
If you give them drugs and sensitize them and ask them to come back a year later, put them in a PET scanner, they are still sensitized a year later, even though they haven't taken drugs in the year since you first sensitized them.
So once you're sensitized, it lasts a long time.
Because you can't unring a bell.
You can't unring this bell.
Conceivably, decades and decades and decades, maybe as we hit later in life, dopamine systems start to die in everybody.
Most of us will never develop Parkinson's disease because the dopamine death is slow and we'll die of something else before we lose enough dopamine to be Parkinson's.
But we are losing it after age 30 or so.
And it may be that later decades, a person can shake what they couldn't shake earlier.
But sensitization is persistent and sometimes it can last decades, I think.
I think so, yes.
For anyone who's sensitized, that's the science behind relapse.
It's a classic story.
Showing 221–240 of 525 · page 12 of 27
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