Dr. Kent Berridge
speaker
525 appearances
1 recordings
1 series
first heard Aug 2026
last heard 4 Aug
Dr. Kent Berridge’s voice in public audio — every appearance, attributed to the second.
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disorders, some people with other behavioral addictions, internets, who are showing in fMRI neuroimaging studies the same kind of limbic hyperreactivity to their addictive cues that a drug addict shows to drug cues.
This is looking like a sensitized response.
The other reason that makes me think this is happening and it's for real is what we mentioned before, that some behavioral addictions like gambling, pornography, and sex pursuit, shopping, drug use, is being created in people who never would have done this before.
That is Parkinson's patients who are being prescribed the direct agonist newer medications in conjunction with L-DOPA, the old medication, that induces behavioral addictions of this sort in anywhere from 10% to 40%.
of people who are taking it, depending on how intense you want to draw the cutoff for these urges.
And if a person shows one of these, the Parkinson's patient shows one of these compulsions, there's a fairly good chance they're going to show a second and a third collection of a constellation, really, of behavioral addictions.
Creating it by dopamine stimulation in...
people who were not at all behavioral addicts before.
This says, yes, it is the same system.
It's following the same rules.
It's the same mesolimbic dopamine system.
It's the same hyper-reactivity to the addictive cues that creates that really intense sensitized want.
Well, I think many of the traditionally effective therapies, they've been mostly cognitive behavioral psychological therapies, 12-step programs, rather than medications before the GLP-1 agonist came along.
Most of these are really not so much calming down the sensitized wanting system, but rather giving ways to cope with it and to deal with it without taking drugs.
mindfulness kinds of approaches where you kind of recognize the cue triggered urge and you feel it, but you look at it, you kind of experience and you don't act on it right away.
You try to put a little space between the urge and the action.
Mesolimbic dopamine systems, they are naturally ready to trigger action.
This is why Parkinson's disease is also associated with dopamine systems.
Motive and motor, that is motive and movement, they kind of go together in the brain and it's naturally one leads to the other.
But cognitive behavioral strategies may give us a way to put a little space between them so we can have the urge and not necessarily act upon it in that way.
Showing 361–380 of 525 · page 19 of 27
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