Dr. Marie-Pierre St-Onge

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773 appearances 1 recordings 1 series first heard Jun 2026 last heard 8 Jun

Dr. Marie-Pierre St-Onge’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · Eating for Better Sleep & Foods that Improve Metabolic Health | Dr. Marie-Pierre St-Onge · 8 Jun 2026 podcast

But it's a real thing, you know, whereas some people like me are kind of more middle of the curve, but, you know, I sit a bit more still unless I'm very caffeinated.

These things add up over time in ways that I think most people underestimate.

But you can do studies, quote unquote, out in the wild with actometry or whatever.

Yes.

A little while ago, I saw a study that said that if you are one night sleep deprived, like you get one or two hours less sleep than normally-

you would get to feel rested.

That it's actually advantageous to exercise because it offsets some of the increase in inflammation.

But then if you're going multiple nights that way, exercising on a regular basis when sleep deprived, it just sets up a susceptibility to illness, susceptibility to injury and so forth.

How much of what you observe under the conditions of sleep deprivation do you think are downstream or upstream of this thing that we just call inflammation?

Like, is this just like a body-wide response and there are a bunch of things that have gone awry?

And so like a bunch of systems are dysregulated or can we pinpoint, okay, when you're sleep deprived,

This is what's happening.

Because I think if women knew that their GLPs were down when they're down on sleep, so that they should expect that they would feel less satiety.

If men knew that their ghrelin levels were elevated when they're down on sleep, that they're going to feel hungrier.

I mean, we have a pretty big prefrontal cortex, most people anyway, and we can intervene simply on the basis of knowledge.

Ultimately, that brings us to the other direction of the equation, right?

How does what we eat impact our sleep?

This is something that I think most people have heard about in the context of try not to eat too close to bedtime.

This is an active debate in many households, actually.

Some people seem to be fine eating close to bedtime and sleeping, even if they track their sleep.

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