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Dr. Mark D'Esposito

๐Ÿ‘ค Speaker
869 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I mean, that's how the pharmaceutical company works.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

SSRIs, too.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I mean, it works, so let's do it.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I'm all for that as a physician.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

But if I had my choice, you know, drugs that boost up multiple cysts, all the catecholamines, the ones that boost up dopamine, epinephrine and norepinephrine, I would steer away from those because you have no control

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

over how you're modulating the system.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Again, I was sort of talking about a cocktail.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

It may be a little bit of dopamine and a little more norepinephrine, but if you take something like Ritalin Adderall, you're just getting the same amount.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So it's kind of, if I was to start to sort of experiment, then I wouldn't use Adderall or Ritalin as the drug that I think would help, even though they're clinically sort of useful.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I use things like bromocriptine and guanfacine where they

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

can modulate a very specific drug.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And then, and then, yeah, then the goal is to, to optimize.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

And that's what we're trying to do with cognitive therapy and everything's sleeping better and better nutrition.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

All of these are aiming to optimize, not, you know, reach some super human potential.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Yeah, it's hard to know.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I mean, I think certain drugs just improve general abilities.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

Either they speed how fast you can process it or how efficient you can process or narrow the focus of your attention, and that just helps all abilities.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

So it's hard to say.

Huberman Lab
Dr. Mark D'Esposito: How to Optimize Cognitive Function & Brain Health

I think there just has to be more work on really understanding what specifically โ€“