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Dr. Mary-Claire King

๐Ÿ‘ค Speaker
417 total appearances

Appearances Over Time

Podcast Appearances

Science Friday
A trailblazing geneticist reflects on her life and work

you won't be able to decide what projects are done.

Science Friday
A trailblazing geneticist reflects on her life and work

You'll be always working for someone else.

Science Friday
A trailblazing geneticist reflects on her life and work

Well, in my particular case, if you don't get a PhD.

Science Friday
A trailblazing geneticist reflects on her life and work

But I think it's generally true that it's very important to stick with it through the discouragements in order to get to the point in whatever field, whether it's medicine or law or science, that you get to decide what the projects will be.

Science Friday
A trailblazing geneticist reflects on her life and work

It's terribly hard to stick it out.

Science Friday
A trailblazing geneticist reflects on her life and work

And I think that one thing that I'm seeing now in students post-pandemic is that the discouragement from the period of the pandemic, the upheaval from that time, the need to be able to turn on a dime more.

Science Friday
A trailblazing geneticist reflects on her life and work

during that time in order to cope with an ever-changing larger environment have made sticking it out even more difficult.

Science Friday
A trailblazing geneticist reflects on her life and work

So I think for people, for those of us of my era, it's very important just to continually encourage people that this has always been true.

Science Friday
A trailblazing geneticist reflects on her life and work

Obviously, the particulars are different, but the need to stick it out

Science Friday
A trailblazing geneticist reflects on her life and work

is really, really important.

Science Friday
A trailblazing geneticist reflects on her life and work

And if you look at all the people that any of us admire historically in whatever field, they're people who stuck it out.

Science Friday
A trailblazing geneticist reflects on her life and work

Of course, I had the world's best mentor in Alan.

Science Friday
A trailblazing geneticist reflects on her life and work

And the main thing that struck me about the project was that I had indeed mastered the electrophoretic techniques that Alan recommended because they were relatively straightforward compared to honest biochemistry that was otherwise going on in his lab.

Science Friday
A trailblazing geneticist reflects on her life and work

And I had got pretty good at them based mostly on the work of Ilo Giblet, the late Ilo Giblet, who was up here in Seattle at the time,

Science Friday
A trailblazing geneticist reflects on her life and work

elegant, elegant protocols for doing all of these experiments.

Science Friday
A trailblazing geneticist reflects on her life and work

So I just followed them as one, in the same way that when I went home, I followed Julia Child.

Science Friday
A trailblazing geneticist reflects on her life and work

I had Julia Child on one side and I had Ido Gibbett on the other.

Science Friday
A trailblazing geneticist reflects on her life and work

Anyway, so I was doing these experiments and the experiments themselves worked, but the results were negative almost all the time.

Science Friday
A trailblazing geneticist reflects on her life and work

That is, the human and chimpanzee proteins for any specific assay that I would apply

Science Friday
A trailblazing geneticist reflects on her life and work

They had the same charge.