Dr. Matt Walker
๐ค SpeakerAppearances Over Time
Podcast Appearances
And he said, we don't really understand it because I've been giving patients this medication and it works to a degree, but something else happens.
They come into the clinic and they say, doc, I don't know.
I'm not having those nightmares anymore.
They seem to have gone away.
And these patients seem to start to show signs of resolution.
So all of a sudden, I had had a model, a clinical model that was in search of data, and he had data that was in search of a theoretical model.
couldn't believe it because it's exactly what I would predict, which is that if noradrenaline is too high in PTSD, you're not processing and stripping the emotion from the memory.
So it keeps coming back over and over like this repetitive nightmare.
But then if you block and help bring back down that level of noradrenaline to that, which would be seen in a normal healthy
In other words, completely blocking it.
All of a sudden, the emotional memory gets the chance to be processed and you finally start to get symptom resolution.
So we couldn't believe it.
He flew down to Berkeley.
We spent several days together.
We went out to dinner.
We just could not stop talking.
He subsequently did some incredible work in this area.
And Prezacin went on to become an FDA-approved medication for PTSD and repetitive nightmares that was approved by the Veterans Administration.
It seems to be, and you can look at this in terms of the electrical activity of REM sleep, the electrical brainwaves of REM sleep in these patients.
And you're right, it doesn't seem to be of the same electrical quality.