Dr. Matthew Hill

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614 appearances 1 recordings 1 series first heard Jul 2024 last heard Jul 2024

Dr. Matthew Hill’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · How Cannabis Impacts Health & the Potential Risks | Dr. Matthew Hill · 8 Jul 2024 podcast

So for some various biological reasons that we don't have a biomarker for, there may be some men that use cannabis and it has a profound effect on their sperm quality, their sperm capacitance, their ability to maintain fertility. And for the bulk majority of men, I'd say that's probably not the case.

But again, if you're someone who is struggling and you use cannabis, male or female, I would say cut that out and see if that has an effect for you.

Yeah, it's very, I mean, I've heard higher numbers than that. In the research literature. No, I've heard higher numbers than that as well. Okay, so I'm on the low end of this. Well, I mean, so I've heard as low as two and I've heard as high as 20.

So first thing, going back to the levels, that's challenging because again, this depends on, are you talking about self-report or are you talking about verified blood levels? Because those have varied. So some of the higher numbers actually come from blood levels where they've taken blood samples and found THC, but the women have reported not using cannabis.

And so the idea that it's like the self-report numbers tend to come in around two or three My guess is the real number is probably somewhere around 10%, but that also is gonna vary depending on what you're talking about because there are a proportion of people who are using cannabis and become pregnant and are unaware they're pregnant and are still using cannabis and that would still qualify

under the way that it's defined, that someone used cannabis while pregnant. So the majority, I would say the overwhelming majority of people, once they learn they're pregnant, now that can be all the way up to almost the end of the first trimester, typically stop using cannabis. That seems to be The norm, I would say. Important point there. Yeah.

And I think also the number that carry on through the entire gestational period is going to be a lot less, I would guess. Now, the motivations for this quite often are more in the capacity of the kind of anti-nauseant qualities that cannabis can have for some people and for women struggling with morning sickness.

Now, anecdotally, I have heard women say, you know, with the history of things like thalidomide and other anti-nauseant drugs that had profound teratogenic effects on the fetuses, women have said that they would rather use cannabis than one of these other compounds because they're less concerned about the impacts of cannabis than they are because of the, you know,

the thalidomide effects that happened.

Yeah, I actually have no idea, but I would imagine. I think it would be one of those hard things to sell, given its history especially. So I think there's a reticence of a lot of people to consider using pharmaceuticals to regulate nausea because they're uncertain of the consequences of it. And they feel that cannabis may be safer.

Now, that in and of itself could present some problems in terms of that thought process. Now, there was also a study that I thought was like some of these things just – It's where they actually decided to call, this was done in Colorado where they called dispensaries and just acted naive and asked what their recommendations were.

And it was something like 80 to 85% of them were actually recommending that people would use cannabis to manage morning sickness. And I thought that was like, it's just one of these disappointing things where you're like, why are you being so wildly irresponsible? to kind of promote these things.

Yeah.

You said it, not me. Could be. I mean, you can balk at either side of this. I think it's... I mean, I have... a lot of frustration in general with the information that bud tenders put out into the world. Is that what they're called, bud tenders? Yeah, bud tenders. That's kind of the colloquial term that people will use for someone who sells cannabis at a dispensary.

We see this in Canada, and I've heard this throughout the States as well. I personally have been a huge advocate for the fact that I think – so I worked in restaurants and bars and stuff when I was younger. And for me to serve alcohol, I had to undergo – I don't know if you do this in the States.

In Canada, you have to do like a – it's like a weekend course essentially called like serving it right or some other terminology where you learn the basics of alcohol, harms, blah, blah, blah, how to tell if someone is intoxicated, when you have to cut them off, all these things that you have to do to be able to serve alcohol. I have no idea if this exists in the States, but –

It was a thing in Canada.

Like anything, even if it's just like an online quiz. So my perspective is because pre-legalization, at least in Canada, there was somewhat of, I think, of a misguided thought that people would leverage their physicians for knowledge about cannabis. And what's become very apparent is that the overwhelming majority of people talk to the people selling them the cannabis.

And yet those people selling cannabis don't need to have undergone any form of education. And so like this kind of kills me because we've worked very hard to try and create educational platforms that are like agnostic in terms of our position on cannabis that are just based on the science.

I'm an executive director of an organization called the Canadian Consortium for the Investigation of Cannabinoids, the CCIC. And we've done CME courses for physicians to try and train them about cannabis because I think it's important that physicians understand this. But

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