Dr. Melissa Ilardo
speaker
791 appearances
1 recordings
1 series
first heard May 2025
last heard May 2025
Dr. Melissa Ilardo’s voice in public audio — every appearance, attributed to the second.
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And so we think that, there's no studies that have shown this yet, but we think that if you're diving, different kind of apnea through pregnancy, that would also increase your risk for these disorders.
And so what we saw was that there was a genetic variant that was actually driving their, like a lowering of their diastolic blood pressure while they were diving.
And so what we saw was that there was a genetic variant that was actually driving their, like a lowering of their diastolic blood pressure while they were diving. And so we think that this is protective against these hypertensive or high blood pressure effects.
And so we think that this is protective against these hypertensive or high blood pressure effects.
It is, yeah. I think we think of it as just snoring, right?
It is, yeah.
I think we think of it as just snoring, right?
Yeah. You're putting yourself into a state of hypoxemia, so your oxygen is very low.
Yeah.
You're putting yourself into a state of hypoxemia, so your oxygen is very low.
Yeah, I mean, I think, well, that's one of the things that we're hoping to find from studying these women.
Yeah, I mean, I think, well, that's one of the things that we're hoping to find from studying these women. So if they've evolved some kind of protective mechanism that protects them in the case of apnea, maybe that's something we could develop into a therapeutic that could be used to help prevent that same hypertensive disorder pregnancy in pregnant women who have apnea for other reasons.
So if they've evolved some kind of protective mechanism that protects them in the case of apnea, maybe that's something we could develop into a therapeutic that could be used to help prevent that same hypertensive disorder pregnancy in pregnant women who have apnea for other reasons.
But otherwise, I would say I think preeclampsia used to be a death sentence for mothers and fetus, which is why it was such a strong driver of evolution.
But otherwise, I would say I think preeclampsia used to be a death sentence for mothers and fetus, which is why it was such a strong driver of evolution. Now I think awareness of it enables treatment, but that's only something that's happened in the last I don't know how many decades. So that's why it could have been such a powerful force in this population.
Now I think awareness of it enables treatment, but that's only something that's happened in the last I don't know how many decades.
So that's why it could have been such a powerful force in this population.
Yeah. I mean, you know, I'm not a maternal health specialist, but I do know that most mutations create non-viable embryos. And so, yeah, that's, I think that could certainly be driving the early miscarriages, especially.
Yeah.
I mean, you know, I'm not a maternal health specialist, but I do know that most mutations create non-viable embryos.
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