Dr. Ori Stollar

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158 appearances 1 recordings 1 series first heard May 2025 last heard May 2025

Dr. Ori Stollar’s voice in public audio — every appearance, attributed to the second.

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Training Without Conflict® | Dog Training Podcast · Episode Fifty-Nine: Dr. Orion · 3 May 2025 podcast

SSRIs don't just increase the serotonin in the brain, because then you don't need SSRIs. You need to take serotonin, and maybe that will kind of go into your brain. They actually change the receptors in the brain. And they change specific receptors in the brain, which will have the behavioral effect. And, and let me Can I stop you?

four to eight weeks. That's actually very, very interesting. And again, if you really want to go into the mechanism of it, I mean, maybe layman because we have a different audience like I would love to hear if someone wants to dig a little bit deeper, I would go with the book by stall the psycho pharmacology book. That's a human psycho pharmacology book by style.

Basically, it's because we're not just... I mean, yes, we're increasing the serotonin at the beginning, but the actual effect is by affecting different 5-HT and serotonin receptors. And some of them are inhibitory receptors, and some of them need to be basically produced. So at the beginning, we actually have very high levels of serotonin, which might...

attached to the inhibitory receptors, which is more associated with, and again, I'm trying not to overcomplicate things because it's complicated, but basically because they attach to specific receptors in the synapses, they cause those side effects. And by the way, there are serotonin receptors in other parts in the body, not just the brain.

So again, they might have other side effects because of that effect. And the changes in the amount of receptors and the sensitivity of those receptors, that changes take longer. So that's why at the beginning when we actually have very high serotonin because of the medication and all of that, we see side effects that are more common in the first two weeks.

then usually we'll see that the side effects are improving, but not necessarily see the actual clinical effect. The clinical effect itself takes between four to eight weeks, like you mentioned. And that's again, that's because of the actual changes in the proteins that are produced and create those receptors in the synapses and that takes a few weeks, and only then we'll see.

But going back to your original question about how we actually know if it's working or not, then a side of how we if it's working or not, but when we say when we say that, the question is, how do we measure that happiness increased?

No, no, no, definitely not. Definitely not. So it really depends on the situation. If we're dealing with a dog, that's, you know, kind of like how you would imagine a person with ADHD. I'm not talking about like playful behavior. I'm talking about the dog that just can't relax. And you know, some some will also say that we don't need to treat ADHD as much.

And it's also there's a rise in how many people are being treated for it. But let's say that if we have a dog that, you know, is, and it is sometimes anxiety can go both ways, it can cause a dog to be hyper all the time, for sure, all over the place. And it can cause the dog to look like, you know, we would use the word depressed, even though we don't really know if it's actually depression. But

it might go to both ways. So yes, sometimes it's a lot easier if you have a depressed dog or those anxious dogs that, you know, are kind of like in a shell and all of a sudden they're coming out of their shell. It's a lot easier to say, oh, yes, it's working. harder sometimes to say, when you have a dog that's all over the place, but also aggressive.

And now he has some reduction in his activity level. And I'm saying some reduction. Yeah, right. When I'm talking to my patients, and I put them on, I recommend having them on a medication like that, or anybody medication, and that might have side effects, I tell them, look, the dog is not supposed to be a zombie. some reduction in energy, that's normal.

I mean, also depends on the dog, the dog's personality, of course, but dogs breed and age. I mean, I wouldn't expect a 10 year old um i don't know a labrador let's let's go with labradors and i wouldn't expect a 10 year old labrador to be as active as a one-year-old labrador right so it's it's different for different uh patients and if you ever had older dogs or even mid-aged dogs you know that

Most of them don't spend the entire day running around and playing and just wanting to be petted all the time or play all the time. Many of them just want to relax. They just want to chill.

um they're questions right they're they're questions it's it's a valid question and and there's a good chance that you know for some of these things unless we'll find a way to you know read the dog's thoughts or something like that we're not gonna know right so again we go according to changes in behavior now it is true all the things that you mentioned there are known side effects in people as well

But there are other studies in people that show that their life are actually improving with the use of these medications. So, you know, yes, they're bad studies or even great studies, but with you know, bad results. I mean, I'm doing like the patient. Yeah, because because, you know, it kind of like doesn't fit the maybe the narrative that psychiatrists will want to say that, yeah, they're safe.

No, we are aware that there are dangers and there are issues. Do dogs can also have, you know, the same things like you're mentioning, like basically deprive them from their joy in life and kind of they're not feeling those things.

there's a good chance that in some dogs yes because again we believe that the brain of people especially with let's say the or the basic emotions does work the same as in in dogs knowing if it's actually exactly the same that's hard to say that's why for example

you know let's say a good example would be autism right so in people there's like the spectrum there are all kinds of different tests that you can do and even genes that are associated with it and in dogs we almost don't have any studies about the topic and not because we don't think that dogs might be autistic i think that most of us believe that there are dogs

that have behavioral issues because they're on the autistic spectrum or the equivalence of that in dogs. But right now we don't have ways to know it. And, you know, again, I wish we had things like measuring something in the blood or like some sort of a scan that will give us the answer, but we don't. So kind of like going back to... Sorry, go ahead.

i'm saying that kind of going back to what we said or what i said at the beginning that in the end we we're both trying i mean both groups right dog trainers and veteran bears are trying to improve not just the dog's life, of course, the dog's life and the owner's life. And if there's any danger to the dog or people around the dog and all of that, of course, we also try to address that.

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