Dr. Peter Attia
speaker
5,258 appearances
36 recordings
6 series
first heard Jan 2024
last heard Jun 2025
Dr. Peter Attia’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsNo recordings in the last 12 months.Older appearances are listed below; set an alert to hear about the next one.
Appearances
Sorry, one other question. Where is the ATP or carbohydrates, whatever the glucose stored in the sperm? Stored probably in the cytoplasm and in the tail. Okay. And it's interesting, when you think about a rocket ship with its payload, it uses a solid fuel, obviously, as opposed to a liquid fuel. It's packaged for that one shot. I assume it's the same here.
There's no transporters to bring glucose in or anything. It has its solid fuel, one shot, go for broke. That's right. Yeah, it is a lot like a rocket, isn't it? It is a lot.
The epididymis is 35 feet if you stretched it out? Roughly, yeah. And just for folks listening- 700 feet of tubules in the testis. The epididymis is on the back of the testis. It's a comma-shaped organ in the back, yeah. Yeah. And we'll come to this, I'm sure, later. This is prone to infection, and that'll probably factor into maybe some of the issues that deal with fertility. Infertility, right.
Yeah.
Meaning there's basically a chemical signal that they need to be able to track to, which I'm assuming is the egg. So the follicular fluid.
So they know exactly where to go. Again, you have to wonder how many years it took to perfect this system, right? You do have to wonder. Do we know what the chemoreceptor is?
Yeah. Do we have anything else that we can?
Yeah. Is there anything like what is the most noxious thing that we can smell with our nose and at what concentration can we detect it? I have no idea. Yeah, because I wonder, just for comparison- Give me a minute. Yeah, yeah, yeah. No, I've always thought about this. I like to hunt. So anyone who's ever bow hunted especially knows that animals can smell at a level that we can't even fathom.
They can smell us literally a mile away if the wind is just blowing their direction. So it's always seemed to me like we have really, really insufficient noses. We were given lots of superpowers in many ways, but smell wasn't really one of them. I think- I would agree with that.
So one part per billion, this is remarkable. So you mentioned that at the base of the epididymis is basically the launchpad. How many are stored in that? Half a billion. Half a billion. So five ejaculations. Yep. Okay. That's a pot. And what's the time to rebuild that? What's the rate at which you fill? Oh, I don't know. We're going to come to this, I'm sure.
But is there a frequency of ejaculation that is too much that if a guy is, say, ejaculating every single day, is that insufficient to get a complete replenishment where if he's having infertility, you would say, you got to move it to every other day or whatever the number is?
To optimize. Right.
but your motility will fall because it's older. There's a min-max curve that you're optimizing for, which you would say is... Three days would be about right.
If ovulation is day 15, how could a day 11 sperm survive four days? It's nurtured once it's past the vagina. But how many of them are surviving? Is it literally the lone wolf or is it the last hundred? Maybe. Some of the sperm bind to the oviduct and wait.
Fallopian tubes.
The fallopian tube, essentially. Yeah.
Because if there's no egg, they'll just sit there. So again, going back to our moon analogy, this is after you've done stage one, stage two, stage three, you're now out of gravity, right? Like it's actually not an energetics problem anymore. Right. Or a death star problem, right? That's right. You've escaped the hostile environment, in this case of gravity. So now it's a fun place.
It's the right pH. It's warm. So do we have a sense? This would be a very interesting experiment. of what is the longest duration that a sperm could survive for conception. In other words, to do the experiment, let's just make it as a thought experiment.
You had a large number of women that you knew were going to ovulate on day 15, and then you would have them have intercourse on day seven, eight, nine, 10, and you create a histoplot or a distribution of what's the frequency of pregnancy across those things and ask what's the bottom fifth percentile, which is the
theoretical possibility yeah that's a good one and then the same thing after you want to develop the bell curve of the whole thing well we know that once the egg is ovulated about eight hours and then it's over this is a very important point it really needs to be front if it's only eight hours of survival after ovulation about eight hours it's dead if it's not this is a very very left tail curve correct ah i did not know that so you want the sperm there ahead of time
Showing 41–60 of 5,258 · page 3 of 263
← Previous
Next →