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Dr. Peter Attia

👤 Speaker
11186 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

What does that mean?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

What does that mean?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Wait a minute, wait a minute. This is impossible for me to fathom. A woman went to her gynecologist and said, I'm having pain with intercourse.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Wait a minute, wait a minute. This is impossible for me to fathom. A woman went to her gynecologist and said, I'm having pain with intercourse.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Any idea how old this woman is?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Any idea how old this woman is?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Okay. And you think this gynecologist doesn't know about estrogen?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Okay. And you think this gynecologist doesn't know about estrogen?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I did in medical school.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I did in medical school.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And you're saying that the reason that this price has come down is, I know Mark is a very hard liner against the PBMs. Did Mark basically take a sledgehammer to that?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And you're saying that the reason that this price has come down is, I know Mark is a very hard liner against the PBMs. Did Mark basically take a sledgehammer to that?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Well, I'm very sorry to hear that story, both at the personal level, but also at the meta level of what is implied. I want to clarify one thing, Rachel. If a woman is on a high enough systemic dose of estradiol, does she also need later in life local estradiol?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Well, I'm very sorry to hear that story, both at the personal level, but also at the meta level of what is implied. I want to clarify one thing, Rachel. If a woman is on a high enough systemic dose of estradiol, does she also need later in life local estradiol?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Has that study been done? That would be a super interesting study. Think of how easy it would be to do a study where you took a group of women that were all at systemic target of estradiol, and you randomized them to a placebo vaginal cream versus an estradiol vaginal cream.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Has that study been done? That would be a super interesting study. Think of how easy it would be to do a study where you took a group of women that were all at systemic target of estradiol, and you randomized them to a placebo vaginal cream versus an estradiol vaginal cream.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You could follow these women for a year if they were in a susceptible enough population, and you would get a very clear answer as to whether or not you're getting additional UTI protection. And if the answer to that is yes, just imagine the implications there. At that point, it becomes malpractice.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You could follow these women for a year if they were in a susceptible enough population, and you would get a very clear answer as to whether or not you're getting additional UTI protection. And if the answer to that is yes, just imagine the implications there. At that point, it becomes malpractice.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Why is DHEA doing it?

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Why is DHEA doing it?