Dr. Peter Hotez

speaker
328 appearances 1 recordings 1 series first heard Jul 2026 last heard 14 Jul

Dr. Peter Hotez’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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So liver fluke, there's two different species.
One is called Clonorchis sinensis.
That's found more in China and Korea.
And then there's Opistoricus viverini, which is in Thailand, Laos, and Cambodia.
What happens is it's acquired by eating uncooked fish.
Not so much as sushi, but what happens is the small fish that the locals use to grind it up, make a fish paste out of it, and they put all sorts of condiments on it and things like that.
But it doesn't kill the parasites.
And it's really ingrained in the food habits of those populations.
It contains the cysts of those worms, of Opus thoracus or Clenorchus.
They come out and then they go into the bile duct.
And they spend years migrating through the bile duct where they'll cause fibrosis or
and cholangitis, but then they caused neoplastic changes in bile duct.
So if you look, the rates of bile duct cancer in Thailand are really high because of that parasite.
That's what's often said.
So as opposed to what we're just talking about, bile duct cancer.
Stomach cancer, probably they're a combination.
I think, you know, what it is also, it's not only the pathogen, like Helicobacter pylori or Opus thoracus, this worm.
It tends to be also the diet, which could be very high in what are called nitrosoamines, which are carcinogenic.
So, for instance, you could actually reproduce that bile duct cancer in laboratory animals.
You give them the parasite, Opus thoracus, and you give them a diet high in nitrosoamines, that one two-punch worm.
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