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Dr. Rhonda Patrick

๐Ÿ‘ค Speaker
8159 total appearances

Appearances Over Time

Podcast Appearances

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

For one, insulin in the brain plays a very important role.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And that role is to basically tell the body how to store fat and how to use energy and whether or not you're satiated after eating a meal.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And what happens is when you're insulin resistant in the brain,

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

it all gets messed up.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And so your body starts to store fat, not as what's called subcutaneous fat, that kind of fat that you can pinch and see.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

It's visceral fat.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

This is the belly fat.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

This is the fat that's deeply surrounding your organs.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

This is the very dangerous type of fat because this fat is metabolically active.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

It is generating inflammation.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

It is

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

constantly being metabolized in what's called free fatty acids, which then cause insulin resistance, right?

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And so what happens is that these individuals, these healthy young men, all of a sudden, even though they didn't really gain much weight on the scale, they gained visceral fat.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And they were no longer satiated.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

So what happens is when you become insulin resistant, both in the brain and in the body, so visceral fat gaining, they were gaining fat around their liver.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

I mean, they were gaining fat, this visceral fat that is really, really dangerous.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

That visceral fat, what happens is every time you eat a meal that's got a lot of glucose, for example, refined ultra processed meal,

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

Your body makes insulin, but you're insulin resistant, so you're not able to respond to that insulin.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And so what happens is your body overcompensates and produces โ€“ your pancreas causes more insulin to be released as an overcompensation to help your body bring that glucose into your muscle or into your adipose tissue.

PBD Podcast
Dr. Rhonda Patrick: Longevity Science, Anti-Aging Hacks & AI Gene Editing | PBD #740

And then what happens is your blood sugar crashes.