Dr. Richard Moulange

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1,784 appearances 1 recordings 1 series first heard Mar 2026 last heard 31 Mar

Dr. Richard Moulange’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Mar 2026 with 1.

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80,000 Hours Podcast · #241 – Richard Moulange on how now AI codes viable genomes from scratch and outperforms virologists at lab work — what could go wrong? · 31 Mar 2026 podcast

So I'm excited to see more work in open weight safeguards.

but only so much more.

At some point we need to call it.

And I think what we really need is like a focused task force or a technical working group that says, okay, we are gonna try as hard as possible for say 12 months.

We're gonna pre-register the best things we're gonna try.

But if we fall short, if the safeguards that we meet, that we generate after more focused effort don't seem to be going anywhere, at some point we have to call it.

Because I really worry that policymakers in and out of government

are still saying, well, we have new open-weight safeguard ideas.

That'll be great.

And I think that the research is tending towards none of them will ever work enough.

There are a lot of different technologies.

I wrote a blog post fairly recently where I listed, I don't know, more than a dozen.

And so when I pick my top, I want to sort of say it's only narrowly my top.

Unfortunately, we're in a world where we're going to need approximately all of them.

It is really about defense in depth.

But ideas that I am particularly excited about, and I'm going to sort of talk about two, but they're very interrelated, are AI-enabled metagenomic biosurveillance and AI-enabled attribution technologies.

Why am I excited about these technologies?

Well, there's a group in Boston, the Nucleic Acid Observatory, and you discussed previously on the podcast.

And they do wastewater and sewage screening for pathogens.

So they collect samples from sewer systems, from airplanes, and they say, well, what sort of pathogens might be there?

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