Dr. Sarah Berry

They have oestrogen-like properties because the structure of these chemicals is similar to oestrogen, so they bind to our oestrogen receptors. So what we know is populations like China and Japan who have a really high intake of soy isoflavones, they have a lower symptom burden. They have a lower prevalence of symptoms.

They have oestrogen-like properties because the structure of these chemicals is similar to oestrogen, so they bind to our oestrogen receptors. So what we know is populations like China and Japan who have a really high intake of soy isoflavones, they have a lower symptom burden. They have a lower prevalence of symptoms.

What we do know, though, is the type of soy isoflavone and the amount is really important. And my colleague, Professor Wendy Hall, has done some great analysis on this where she's looked at all of the different studies. And what we know is that there's a particular type of soy isoflavone called genistein.

What we do know, though, is the type of soy isoflavone and the amount is really important. And my colleague, Professor Wendy Hall, has done some great analysis on this where she's looked at all of the different studies. And what we know is that there's a particular type of soy isoflavone called genistein.

What we do know, though, is the type of soy isoflavone and the amount is really important. And my colleague, Professor Wendy Hall, has done some great analysis on this where she's looked at all of the different studies. And what we know is that there's a particular type of soy isoflavone called genistein.

And that if your supplement has genistein at or above 15 milligrams per day, that's where we seem to see a consistent beneficial effect. If, however, it has a lower amount than that, it's unlikely for the majority of people. to have a big effect. And then there's one last really interesting element to this.

And that if your supplement has genistein at or above 15 milligrams per day, that's where we seem to see a consistent beneficial effect. If, however, it has a lower amount than that, it's unlikely for the majority of people. to have a big effect. And then there's one last really interesting element to this.

And that if your supplement has genistein at or above 15 milligrams per day, that's where we seem to see a consistent beneficial effect. If, however, it has a lower amount than that, it's unlikely for the majority of people. to have a big effect. And then there's one last really interesting element to this.

We know that also how you respond to soy isoflavones differs from one person to the other, and this is where the microbiome comes in, and I think is really exciting. So we have species in our gut, in our microbiome, that metabolize these soy isoflavones, and they can metabolize them to a really active form that binds really strongly to the receptors.

We know that also how you respond to soy isoflavones differs from one person to the other, and this is where the microbiome comes in, and I think is really exciting. So we have species in our gut, in our microbiome, that metabolize these soy isoflavones, and they can metabolize them to a really active form that binds really strongly to the receptors.

We know that also how you respond to soy isoflavones differs from one person to the other, and this is where the microbiome comes in, and I think is really exciting. So we have species in our gut, in our microbiome, that metabolize these soy isoflavones, and they can metabolize them to a really active form that binds really strongly to the receptors.

And these bacteria are called equol producers because from the soy isoflavone, they produce another chemical called equol. And this particular chemical is a really strong estrogen-like compound. It binds to the estrogen receptor really strongly. What we know is if you're an equol producer,

And these bacteria are called equol producers because from the soy isoflavone, they produce another chemical called equol. And this particular chemical is a really strong estrogen-like compound. It binds to the estrogen receptor really strongly. What we know is if you're an equol producer,

And these bacteria are called equol producers because from the soy isoflavone, they produce another chemical called equol. And this particular chemical is a really strong estrogen-like compound. It binds to the estrogen receptor really strongly. What we know is if you're an equol producer,

So if you metabolize the soy isoflavones to Equal and you're supplemented with soy isoflavones, you have a 75% greater reduction in symptoms than if you're not an Equal producer. And the reason I want to mention that Drew is because that takes me back to my point a few minutes ago that everyone will respond differently. So for example,

So if you metabolize the soy isoflavones to Equal and you're supplemented with soy isoflavones, you have a 75% greater reduction in symptoms than if you're not an Equal producer. And the reason I want to mention that Drew is because that takes me back to my point a few minutes ago that everyone will respond differently. So for example,

So if you metabolize the soy isoflavones to Equal and you're supplemented with soy isoflavones, you have a 75% greater reduction in symptoms than if you're not an Equal producer. And the reason I want to mention that Drew is because that takes me back to my point a few minutes ago that everyone will respond differently. So for example,

If I went and started taking soy isoflavones and I'm not an equal producer, but my best friend started taking soy isoflavones and she had the gut microbiome species that enable her to produce equal, she is going to see a huge benefit. I'm not going to see such a big benefit. But that means that I shouldn't be advising her not to take it just because it doesn't work for me.

If I went and started taking soy isoflavones and I'm not an equal producer, but my best friend started taking soy isoflavones and she had the gut microbiome species that enable her to produce equal, she is going to see a huge benefit. I'm not going to see such a big benefit. But that means that I shouldn't be advising her not to take it just because it doesn't work for me.

If I went and started taking soy isoflavones and I'm not an equal producer, but my best friend started taking soy isoflavones and she had the gut microbiome species that enable her to produce equal, she is going to see a huge benefit. I'm not going to see such a big benefit. But that means that I shouldn't be advising her not to take it just because it doesn't work for me.