Dr. Siddhartha Mukherjee
speaker
438 appearances
1 recordings
1 series
first heard Jul 2026
last heard 23 Jul
Dr. Siddhartha Mukherjee’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
Molecule by molecule, they figure out what the targets are, they validate those targets, and then they build a medicine by stitching together, literally stitching together a molecule in space that can either jam a lock in a key in a cancer-relevant target.
So that's what we're doing at Manus.
We have taught the algorithm.
The algorithm actually knows more medicinal chemistry than I do.
And it speaks to us, it speaks back to us by producing, this is the funny thing about it, it speaks the language of medicinal chemistry.
So if you give it a potential target or a query,
it will start generating not one, not two, not three, but series of medicines that it's been built using the laws of chemistry and physics, these constraints.
And then, of course, we have to test them in real life and then feed that information back to AI and say, yes, you're wrong there, you're right there, you're wrong there.
And that's called reinforcement learning.
You learn.
And I think that is the capacity to really change the game.
We used to build medicines one at a time using human medicinal chemists.
That's not good enough.
We need to do better.
So we're making medicines many at a time using AI medicinal chemistry.
Not in the simple way you think.
I mean, I think the problem with, I mean, I applaud people who have
incredibly positive attitudes through their cancers.
I think it's wonderful, but it also unfortunately creates a kind of a prison cell of optimism for patients who don't have a positive attitude.
You may be suffering from terrible grief because you're worried about leaving your children behind.
Showing 361–380 of 438 · page 19 of 22
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