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Dr. Stacy Sims

πŸ‘€ Speaker
3375 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And then we have time-restricted eating, and that's the fancy way of saying normal eating, where you're having breakfast and then you stop eating after or you don't have anything after dinner, right? So you're eating with your circadian rhythm during the day.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And then we have time-restricted eating, and that's the fancy way of saying normal eating, where you're having breakfast and then you stop eating after or you don't have anything after dinner, right? So you're eating with your circadian rhythm during the day.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

If we look at intermittent fasting where you're holding the fast up till noon or you're having days of really low calorie restriction, we see in active women it's very detrimental, right? unless you have PCOS or you have some other subclinical issue. And the reason for that is we, as women, have more oxidative fibers.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

If we look at intermittent fasting where you're holding the fast up till noon or you're having days of really low calorie restriction, we see in active women it's very detrimental, right? unless you have PCOS or you have some other subclinical issue. And the reason for that is we, as women, have more oxidative fibers.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

If we look at intermittent fasting where you're holding the fast up till noon or you're having days of really low calorie restriction, we see in active women it's very detrimental, right? unless you have PCOS or you have some other subclinical issue. And the reason for that is we, as women, have more oxidative fibers.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So we hear about all the things about fasting to improve our metabolic flexibility, to improve telomere length, to improve parasympathetic activation. But by the nature of women having more oxidative fibers, we are already metabolically more flexible than men.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So we hear about all the things about fasting to improve our metabolic flexibility, to improve telomere length, to improve parasympathetic activation. But by the nature of women having more oxidative fibers, we are already metabolically more flexible than men.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So we hear about all the things about fasting to improve our metabolic flexibility, to improve telomere length, to improve parasympathetic activation. But by the nature of women having more oxidative fibers, we are already metabolically more flexible than men.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Sure, sure. So oxidative fibers are muscle fibers that are more aerobic capacity. So those are the ones that you can go long and slow for very... long period of time because it uses a lot of free fatty acids, you need a little bit of glucose in order to activate those free fatty acids.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Sure, sure. So oxidative fibers are muscle fibers that are more aerobic capacity. So those are the ones that you can go long and slow for very... long period of time because it uses a lot of free fatty acids, you need a little bit of glucose in order to activate those free fatty acids.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Sure, sure. So oxidative fibers are muscle fibers that are more aerobic capacity. So those are the ones that you can go long and slow for very... long period of time because it uses a lot of free fatty acids, you need a little bit of glucose in order to activate those free fatty acids.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So when we look when a woman starts to exercise, she goes through blood glucose first and then gets into free fatty acid use, she doesn't tap so much into liver muscle glycogen, which is I think another misconception that happens. So when we're talking about fasting or fasted workouts, trying to improve that metabolic flexibility, it increases stress on the woman.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So when we look when a woman starts to exercise, she goes through blood glucose first and then gets into free fatty acid use, she doesn't tap so much into liver muscle glycogen, which is I think another misconception that happens. So when we're talking about fasting or fasted workouts, trying to improve that metabolic flexibility, it increases stress on the woman.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So when we look when a woman starts to exercise, she goes through blood glucose first and then gets into free fatty acid use, she doesn't tap so much into liver muscle glycogen, which is I think another misconception that happens. So when we're talking about fasting or fasted workouts, trying to improve that metabolic flexibility, it increases stress on the woman.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And so when we're talking about overall stress, we're talking about cortisol increase, and they can't hit intensities high enough with no fuel to be able to invoke the post-exercise responses of growth hormone and testosterone, which then drop cortisol. So from an overall stress perspective, that fasted workout and holding that fast for a long period of time increases cortisol.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And so when we're talking about overall stress, we're talking about cortisol increase, and they can't hit intensities high enough with no fuel to be able to invoke the post-exercise responses of growth hormone and testosterone, which then drop cortisol. So from an overall stress perspective, that fasted workout and holding that fast for a long period of time increases cortisol.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And so when we're talking about overall stress, we're talking about cortisol increase, and they can't hit intensities high enough with no fuel to be able to invoke the post-exercise responses of growth hormone and testosterone, which then drop cortisol. So from an overall stress perspective, that fasted workout and holding that fast for a long period of time increases cortisol.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

But then when we look from like a hypothalamic point of view and we're looking at how the brain reads it, so we know that there's one area of cis-peptin neurons in the brain for men, but there are two for women. So the two areas are distinct where one controls appetite and luteinizing hormone and the other one is looking at estrogen and thyroid.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

But then when we look from like a hypothalamic point of view and we're looking at how the brain reads it, so we know that there's one area of cis-peptin neurons in the brain for men, but there are two for women. So the two areas are distinct where one controls appetite and luteinizing hormone and the other one is looking at estrogen and thyroid.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

But then when we look from like a hypothalamic point of view and we're looking at how the brain reads it, so we know that there's one area of cis-peptin neurons in the brain for men, but there are two for women. So the two areas are distinct where one controls appetite and luteinizing hormone and the other one is looking at estrogen and thyroid.