Dr. Stephanie Venn-Watson

So let's work through that to make these discoveries. And when we get to these longevity must-haves, we're now able to, you know, a lot of longevity research is on short-lived species of how do we help mice and worms live longer.

And it doesn't really translate, right?

And it doesn't really translate, right?

And it doesn't really translate, right?

So, you know, Nick really, Nick and I really came in and we're like, oh my gosh, we have this incredible opportunity. Nature's already figured it out, right, Mark? I mean, nature's already figured out how a mammal can live 27, 30 times longer because humans and dolphins and elephants live a lot longer than a mouse. So why?

So, you know, Nick really, Nick and I really came in and we're like, oh my gosh, we have this incredible opportunity. Nature's already figured it out, right, Mark? I mean, nature's already figured out how a mammal can live 27, 30 times longer because humans and dolphins and elephants live a lot longer than a mouse. So why?

So, you know, Nick really, Nick and I really came in and we're like, oh my gosh, we have this incredible opportunity. Nature's already figured it out, right, Mark? I mean, nature's already figured out how a mammal can live 27, 30 times longer because humans and dolphins and elephants live a lot longer than a mouse. So why?

So let's figure out what, how evolution has already enabled massive longevity, enabling tap into that and then make it even better.

So let's figure out what, how evolution has already enabled massive longevity, enabling tap into that and then make it even better.

So let's figure out what, how evolution has already enabled massive longevity, enabling tap into that and then make it even better.

So it was just like, let's focus on these species, not to dismiss the short list, the basic science, but it's an unlock. So the seven must-haves of longevity, and this is assuming that longevity, the way we define it is as a geroprotector, so a molecule that slows our aging rate and therefore slows the onset of the chronic diseases that kill us.

So it was just like, let's focus on these species, not to dismiss the short list, the basic science, but it's an unlock. So the seven must-haves of longevity, and this is assuming that longevity, the way we define it is as a geroprotector, so a molecule that slows our aging rate and therefore slows the onset of the chronic diseases that kill us.

So it was just like, let's focus on these species, not to dismiss the short list, the basic science, but it's an unlock. So the seven must-haves of longevity, and this is assuming that longevity, the way we define it is as a geroprotector, so a molecule that slows our aging rate and therefore slows the onset of the chronic diseases that kill us.

healthier, and then by default, be able to extend your own longevity so that you can live longer. So of those, the seven longevity must-haves are first, this molecule needs to tap into the longevity-regulating pathway. It's this complicated keg, it's called the keg pathway, and it's based upon a hypocaloric diet.

healthier, and then by default, be able to extend your own longevity so that you can live longer. So of those, the seven longevity must-haves are first, this molecule needs to tap into the longevity-regulating pathway. It's this complicated keg, it's called the keg pathway, and it's based upon a hypocaloric diet.

healthier, and then by default, be able to extend your own longevity so that you can live longer. So of those, the seven longevity must-haves are first, this molecule needs to tap into the longevity-regulating pathway. It's this complicated keg, it's called the keg pathway, and it's based upon a hypocaloric diet.

So caloric restriction and the whole pathway that's been built out on how caloric restriction works extends longevity across multiple species. At the heart of it is activating AMPK and inhibiting mTOR, which, as you had mentioned, metformin activates AMPK and rapamycin inhibits mTOR. C15 does both. So that was really exciting to see. It's really hitting at the heart as other longevity molecules.

So caloric restriction and the whole pathway that's been built out on how caloric restriction works extends longevity across multiple species. At the heart of it is activating AMPK and inhibiting mTOR, which, as you had mentioned, metformin activates AMPK and rapamycin inhibits mTOR. C15 does both. So that was really exciting to see. It's really hitting at the heart as other longevity molecules.

So caloric restriction and the whole pathway that's been built out on how caloric restriction works extends longevity across multiple species. At the heart of it is activating AMPK and inhibiting mTOR, which, as you had mentioned, metformin activates AMPK and rapamycin inhibits mTOR. C15 does both. So that was really exciting to see. It's really hitting at the heart as other longevity molecules.

The second is that it needs to target these... And just to back up on that for a minute, because people might not understand that.