Dr. Stephanie Venn-Watson
๐ค SpeakerAppearances Over Time
Podcast Appearances
So we did, Nick, Shark and I, we did a study showing dolphins that, showing what hadn't yet been proven before, which is if you take individuals within the same population, that there will be some that age at different rates, despite having a relatively controlled environment. And it was crystal clear in the dolphins that we had fast aging and slow aging dolphins.
So we did, Nick, Shark and I, we did a study showing dolphins that, showing what hadn't yet been proven before, which is if you take individuals within the same population, that there will be some that age at different rates, despite having a relatively controlled environment. And it was crystal clear in the dolphins that we had fast aging and slow aging dolphins.
it ends up the aging rate biomarker for that was hemoglobin. And that had to do with, again, fragile cells in which they were increasingly losing red blood cell health over time. One measurement of that is called red blood cell distribution with, or RDW, which has become โ see, there you go โ a really popular way of โ understanding aging rate is RDW. So we saw that crystal clear in the dolphins.
it ends up the aging rate biomarker for that was hemoglobin. And that had to do with, again, fragile cells in which they were increasingly losing red blood cell health over time. One measurement of that is called red blood cell distribution with, or RDW, which has become โ see, there you go โ a really popular way of โ understanding aging rate is RDW. So we saw that crystal clear in the dolphins.
it ends up the aging rate biomarker for that was hemoglobin. And that had to do with, again, fragile cells in which they were increasingly losing red blood cell health over time. One measurement of that is called red blood cell distribution with, or RDW, which has become โ see, there you go โ a really popular way of โ understanding aging rate is RDW. So we saw that crystal clear in the dolphins.
Right, that's a pretty bold claim. So we put the stake.
Right, that's a pretty bold claim. So we put the stake.
Right, that's a pretty bold claim. So we put the stake.
It's been a long time, exactly. So we put the stake at the ground back in 2020, and we published that in Nature's Scientific Reports. This last year has been really exciting, Mark.
It's been a long time, exactly. So we put the stake at the ground back in 2020, and we published that in Nature's Scientific Reports. This last year has been really exciting, Mark.
It's been a long time, exactly. So we put the stake at the ground back in 2020, and we published that in Nature's Scientific Reports. This last year has been really exciting, Mark.
There have been now to date three other independent teams that have evaluated C15 as meeting the criteria of essentiality, all using different methods of gold standard methods of looking at pregnant mice and saying, hey, if you make the mom C15 deficient, Does her neonate show evidence of a nutritional deficiency? And the answer was yes.
There have been now to date three other independent teams that have evaluated C15 as meeting the criteria of essentiality, all using different methods of gold standard methods of looking at pregnant mice and saying, hey, if you make the mom C15 deficient, Does her neonate show evidence of a nutritional deficiency? And the answer was yes.
There have been now to date three other independent teams that have evaluated C15 as meeting the criteria of essentiality, all using different methods of gold standard methods of looking at pregnant mice and saying, hey, if you make the mom C15 deficient, Does her neonate show evidence of a nutritional deficiency? And the answer was yes.
And when you give it just C15, does a nutritional deficiency, is it fixed? And the answer was yes.
And when you give it just C15, does a nutritional deficiency, is it fixed? And the answer was yes.
And when you give it just C15, does a nutritional deficiency, is it fixed? And the answer was yes.
Poor growth and poor neural development. It ends up that epidemiologically we're seeing the same trend disturbingly in humans. That if mom has lower C15 levels, her baby gets lower C15. And lower C15 now has been associated with poor body growth, poor brain development, even up to cognitive development of kids up to six years old. The upside, right? What's...
Poor growth and poor neural development. It ends up that epidemiologically we're seeing the same trend disturbingly in humans. That if mom has lower C15 levels, her baby gets lower C15. And lower C15 now has been associated with poor body growth, poor brain development, even up to cognitive development of kids up to six years old. The upside, right? What's...
Poor growth and poor neural development. It ends up that epidemiologically we're seeing the same trend disturbingly in humans. That if mom has lower C15 levels, her baby gets lower C15. And lower C15 now has been associated with poor body growth, poor brain development, even up to cognitive development of kids up to six years old. The upside, right? What's...