Dr. Steven Novella

speaker

11,445 appearances 18 recordings 2 series first heard Mar 2026 last heard 2d ago

Dr. Steven Novella’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 18 in all, peaking in Aug 2026 with 5.

Appearances

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The Skeptics' Guide to the Universe · The Skeptics Guide #1063 - Nov 22 2025 podcast

So again, this is the kind of thing where a physician who's familiar with this kind of research would instantly see that, oh yeah, they didn't compare it to other diseases, right? voice-verified

So if you're saying it's specific to chronic fatigue syndrome – voice-verified

then you have to show that it doesn't exist in everybody with any disease. voice-verified

You know what I mean? voice-verified

Just saying it doesn't exist, these markers aren't present in healthy controls, that's one important component, but you also need to show it's not present in people who have, let's say, rheumatoid arthritis, or who have Parkinson's disease, or Alzheimer's disease, or MS, or a hundred other diseases. voice-verified

You give us some idea that it's actually specific to chronic fatigue syndrome. voice-verified

What if it's present in all of these things? voice-verified

Well, then maybe it's just a marker for inflammation, right? voice-verified

How do we know that they didn't just discover some other marker for inflammation that's going to occur in any chronic illness or in many chronic illnesses? voice-verified

Or what if this is a marker for the depression that people often feel from the chronic fatigue that's secondary to the chronic fatigue and then becomes comorbid with it? voice-verified

So... voice-verified

Who knows, right? voice-verified

We can't answer any of these questions because all they did was compare it to healthy controls. voice-verified

So this is just getting the ball started. voice-verified

This is the kind of thing where, again, this is saying, oh, there's something potentially here. voice-verified

Now here's a dozen other studies we need to do to really suss this out. voice-verified

We need to confirm it. voice-verified

We need larger data. voice-verified

We need a more generalizable population. voice-verified

We need to validate that it's unique to or telling us something specific about chronic fatigue syndrome. voice-verified

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