Dr. Ted Achacoso
speaker
679 appearances
10 recordings
1 series
first heard Jun 2026
last heard 2 Sep
Dr. Ted Achacoso’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 10 in all, peaking in Jul 2026 with 4.
Appearances
anymore.
It's enteric microbiota, gut and brain at the metalumbic level.
Therefore, the $64,000 clinical question of the day is why treat depression exclusively in the brain when the signal starts in your gut?
Let us unpack the exact biochemical and cellular mechanisms behind this connection.
To understand this jury, we must look at the gut microbiota through the lens of the term holobiontology, which means simply means that the human is not an isolated organism, but is an entire ecosystem of cells, right?
And symbiotic microbes.
Within this ecosystem, gut microbes are f active metabolic factories.
They ferment dietary fibers into short chain fatty acids.
Or SCFAs such as acetate, propionate, butyrate.
These SCFAs are not just local fuel.
They are potent epigenetic signaling molecules.
Butyrate, for instance, asks as a histone deacetyles inhibitor, crossing the broad brain barrier to upregulate brain-derived neurotropic factor or BDNF in the hippocampus, directly supporting synaptic plasticity and mood regulation.
Lots of charge.
But simply put, it means that there are molecules in the gut that drive the brain to influence your mood.
When
When the gut microbiota shifts into a state of dysbiosis, right?
Uh, dysbiosis is merely a shorthand for that word dysbacteriosis.
This is due to cynobiotic exposure.
And cynobiotics are things that have never been encountered by your body before.
Evolution, like your new drugs, glyphosate or uh chronic psychological stress, the protective mucosal barrier is compromised.
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