Dr. Todd LePine
👤 PersonAppearances Over Time
Podcast Appearances
And they always say- I like The Lost.
And they always say- I like The Lost.
It's a little bit different. There's a little more raunchiness. With Survivor, you're just kind of trying to make it to a road somewhere. But the point was that he always, this guy on the Survivor show, would always say, if the water's not moving, don't drink it. If the water's flowing fast, drink it because it's cleaner. And the same thing with the small bowel. If the small bowel stagnates,
It's a little bit different. There's a little more raunchiness. With Survivor, you're just kind of trying to make it to a road somewhere. But the point was that he always, this guy on the Survivor show, would always say, if the water's not moving, don't drink it. If the water's flowing fast, drink it because it's cleaner. And the same thing with the small bowel. If the small bowel stagnates,
It's a little bit different. There's a little more raunchiness. With Survivor, you're just kind of trying to make it to a road somewhere. But the point was that he always, this guy on the Survivor show, would always say, if the water's not moving, don't drink it. If the water's flowing fast, drink it because it's cleaner. And the same thing with the small bowel. If the small bowel stagnates,
it becomes swampy and bacteria grow in it. And the same thing is happening in the human small intestine. And so it's a sequence. So food poisoning, the antibodies, and then you develop the bacterial buildup.
it becomes swampy and bacteria grow in it. And the same thing is happening in the human small intestine. And so it's a sequence. So food poisoning, the antibodies, and then you develop the bacterial buildup.
it becomes swampy and bacteria grow in it. And the same thing is happening in the human small intestine. And so it's a sequence. So food poisoning, the antibodies, and then you develop the bacterial buildup.
The interesting thing about contrasting IBD to IBS, so the antibody that we discovered is an autoantibody that is directly related to the pathology. So the higher that antibody is, the sicker you are. The antibodies in IBD are markers of IBD. They're not directly implicated in the pathophysiology. The antibody to vinculin that we discovered is directly related to the pathophysiology.
The interesting thing about contrasting IBD to IBS, so the antibody that we discovered is an autoantibody that is directly related to the pathology. So the higher that antibody is, the sicker you are. The antibodies in IBD are markers of IBD. They're not directly implicated in the pathophysiology. The antibody to vinculin that we discovered is directly related to the pathophysiology.
The interesting thing about contrasting IBD to IBS, so the antibody that we discovered is an autoantibody that is directly related to the pathology. So the higher that antibody is, the sicker you are. The antibodies in IBD are markers of IBD. They're not directly implicated in the pathophysiology. The antibody to vinculin that we discovered is directly related to the pathophysiology.
We can make rats have IBS just by giving them this toxin. And so that's very cool because it allows us to study new drugs and new therapies coming in.
We can make rats have IBS just by giving them this toxin. And so that's very cool because it allows us to study new drugs and new therapies coming in.
We can make rats have IBS just by giving them this toxin. And so that's very cool because it allows us to study new drugs and new therapies coming in.
Well, the four horsemen of the apocalypse of IBS are Campylobacter, Salmonella, Shigella, and some E. coli, food poisoning type of E. coli, pathogenic E. coli. Giardia can do it too. It turns out it has vinculin in its structure. And so maybe that's how you get the antibodies from Giardia. The viruses are less likely to precipitate IBS.
Well, the four horsemen of the apocalypse of IBS are Campylobacter, Salmonella, Shigella, and some E. coli, food poisoning type of E. coli, pathogenic E. coli. Giardia can do it too. It turns out it has vinculin in its structure. And so maybe that's how you get the antibodies from Giardia. The viruses are less likely to precipitate IBS.
Well, the four horsemen of the apocalypse of IBS are Campylobacter, Salmonella, Shigella, and some E. coli, food poisoning type of E. coli, pathogenic E. coli. Giardia can do it too. It turns out it has vinculin in its structure. And so maybe that's how you get the antibodies from Giardia. The viruses are less likely to precipitate IBS.
So the four horsemen, Campylobacter salmonella, Shigella, and E. coli. So that's... And it occurs about starts to occur about three months after you get sick. Patients will remember. Some don't remember. And they'll say, you know, they have a couple of days of diarrhea and they don't pay much attention to it.
So the four horsemen, Campylobacter salmonella, Shigella, and E. coli. So that's... And it occurs about starts to occur about three months after you get sick. Patients will remember. Some don't remember. And they'll say, you know, they have a couple of days of diarrhea and they don't pay much attention to it.
So the four horsemen, Campylobacter salmonella, Shigella, and E. coli. So that's... And it occurs about starts to occur about three months after you get sick. Patients will remember. Some don't remember. And they'll say, you know, they have a couple of days of diarrhea and they don't pay much attention to it.