Dr. Tommy Wood

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1,133 appearances 1 recordings 1 series first heard Jul 2026 last heard 20 Jul

Dr. Tommy Wood’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · Accelerate Learning & Increase Cognitive Capacity | Dr. Tommy Wood · 20 Jul 2026 podcast

Test your homocysteine levels, which is a marker of B vitamin status, which we know is a

risk factor for cognitive decline dementia as well so if um if you can test your levels and it shows that you need more and yes there are the the normal ranges that you have on a blood test are not necessarily the same as the risk ranges so um homocysteine is a good example

a normal range for homocysteine, which goes up if you need some of these methylation-dependent B vitamins, the normal range might go up to like 15 or 16.

But we know that risk is definitely elevated above 13 and is probably elevated above sort of 10 to 11.

So what your target range really might be is it's probably lower than what the normal range might be.

But we have very good evidence that if you then supplement

when somebody is above that range and you bring that down, you see significant improvements in cognitive function or slowed cognitive decline.

That is particularly the case for omega-3s and B vitamins that lower homocysteine.

And so this is the interactions that you were talking about earlier.

And this is the best one that we know of, although I'm sure there are many more.

Like I said, there are lots of trials that have given

omega-3s or have given B vitamins to lower homocysteine and just haven't seen much of an effect.

And everybody goes, oh, well, they don't work.

But there are now at least three randomized controlled trials that have shown that omega-3 status and B vitamin status interact and they're dependent on one another.

So if you give

B vitamins to somebody who has elevated homocysteine, you bring down their homocysteine, but they have poor omega-3 levels, you don't see any benefit.

And that's been shown in two trials.

It was originally shown in the Vitacog trial that was run out of the University of Oxford.

It was then replicated in the B-proof trial.

Then the other side has also been shown.

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